Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | KLK7 | P49862 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7747296 | 0.95 | TSHR (0.38) | TSHRMEN1KMT2AMAPTATM | |
| SCHEMBL7747291 | 0.95 | TSHR (0.38) | TSHRMEN1KMT2AMAPTATM | |
| SCHEMBL7747301 | 0.95 | TSHR (0.38) | TSHRMEN1KMT2AMAPTATM | |
| SCHEMBL30258554 | 0.88 | TSHR (0.44) | TSHRKMT2AMAPTALDH1A1TDP1 | |
| SCHEMBL698490 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL14167163 | 0.85 | TSHR (0.52) | TSHRMEN1KMT2AMAPTATM | |
| SCHEMBL2478048 | 0.83 | BRD4 (0.42) | TSHRMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL7746087 | 0.80 | ALDH1A1 (0.40) | TSHRMEN1KMT2AMAPTATM | |
| SCHEMBL7746092 | 0.80 | ALDH1A1 (0.40) | TSHRMEN1KMT2AMAPTATM | |
| SCHEMBL8359776 | 0.80 | ALDH1A1 (0.40) | TSHRMEN1KMT2AMAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827849-A | HAVING INHIBITORY EFFECT ON INFLAMMATION AND BONE DEGRADATION, ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASIS-INHIBITING EFFECT | KARL THOMAE GMBH (DE) | 1998-10-27 | — | — | US | disclosed |