Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 18/20 | 0.41 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.41 |
| ▸ | CTSD | P07339 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | CASP9 | P55211 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30193475 | 0.93 | BACE1 (0.41) | BACE1BACE2CTSD | |
| SCHEMBL7555807 | 0.93 | ENPEP (0.42) | BACE1CTSDCASP1CASP3CASP9 | |
| SCHEMBL30561495 | 0.91 | ERAP2 (0.40) | BACE1BACE2 | |
| SCHEMBL30913884 | 0.90 | BACE1 (0.40) | BACE1CTSDCASP3CASP7 | |
| SCHEMBL30913885 | 0.90 | BACE1 (0.40) | BACE1CTSDCASP3CASP7 | |
| SCHEMBL30476106 | 0.89 | BACE1 (0.49) | BACE1BACE2CTSD | |
| SCHEMBL30974548 | 0.88 | BACE1 (0.35) | BACE1CASP3CASP7 | |
| SCHEMBL30720017 | 0.88 | BACE1 (0.46) | BACE1BACE2CTSD | |
| SCHEMBL30781078 | 0.87 | MME (0.36) | — | |
| SCHEMBL30781160 | 0.87 | MME (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230053463-A1 | ABALOPARATIDE FORMULATIONS AND METHODS OF TESTING, STORING, MODIFYING, AND USING SAME | RADIUS HEALTH, INC. (US) | 2023-02-23 | — | — | US | disclosed |