Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 16/20 | 0.60 |
| ▸ | CTSD | P07339 | 2/20 | 0.57 |
| ▸ | BACE2 | Q9Y5Z0 | 4/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32670512 | 0.94 | BACE1 (0.54) | BACE1CTSDBACE2 | |
| SCHEMBL29398845 | 0.90 | BACE1 (0.69) | BACE1CTSDBACE2 | |
| SCHEMBL30931573 | 0.88 | OPRD1 (0.53) | — | |
| SCHEMBL30258973 | 0.87 | BACE1 (0.70) | BACE1CTSDBACE2 | |
| SCHEMBL31487875 | 0.87 | BACE1 (0.56) | BACE1CTSDBACE2 | |
| SCHEMBL30974021 | 0.87 | BACE1 (0.53) | BACE1CTSDBACE2 | |
| SCHEMBL30198937 | 0.86 | BACE1 (0.73) | BACE1CTSDBACE2 | |
| SCHEMBL30567793 | 0.86 | BACE1 (0.67) | BACE1CTSDBACE2 | |
| SCHEMBL29506418 | 0.85 | BACE1 (0.73) | BACE1CTSDBACE2 | |
| SCHEMBL30607497 | 0.84 | BACE1 (0.66) | BACE1CTSDBACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3443096-B1 | COMPOSITIONS AND METHODS FOR SELECTIVE EXPRESSION OF CHIMERIC ANTIGEN RECEPTORS | NOVARTIS AG (CH) | 2023-03-01 | — | — | EP | claimed |