Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23264024 | 0.79 | ADORA2A (0.35) | ADORA2AADORA2BTSHRDYRK1A | |
| SCHEMBL562141 | 0.73 | ADORA2A (0.47) | ADORA2AADORA2BDYRK1A | |
| SCHEMBL5681952 | 0.71 | ADORA2A (0.53) | ADORA2AADORA2BDYRK1A | |
| SCHEMBL11970930 | 0.69 | ADORA2A (0.47) | ADORA2AADORA2B | |
| SCHEMBL20298327 | 0.68 | ADORA2A (0.38) | ADORA2AADORA2BTSHR | |
| SCHEMBL30409315 | 0.68 | CYP1A2 (0.35) | ADORA2AADORA2BTSHR | |
| SCHEMBL25515475 | 0.68 | CYP1A2 (0.35) | ADORA2AADORA2BTSHR | |
| SCHEMBL8415606 | 0.68 | ADORA2A (0.50) | ADORA2AADORA2BDYRK1A | |
| SCHEMBL11976715 | 0.67 | DYRK1A (0.62) | ADORA2AADORA2BDYRK1A | |
| SCHEMBL21058167 | 0.66 | LMNA (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023043836-A1 | HSD17B13 INHIBITORS AND USES THEREOF | METACRINE, INC. (US) | 2023-03-23 | — | — | WO | disclosed |