Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | CCNK | O75909 | 12/20 | 0.49 |
| ▸ | CDK12 | Q9NYV4 | 12/20 | 0.49 |
| ▸ | CCNT1 | O60563 | 11/20 | 0.49 |
| ▸ | CDK9 | P50750 | 11/20 | 0.49 |
| ▸ | CCNE1 | P24864 | 10/20 | 0.49 |
| ▸ | CDK2 | P24941 | 10/20 | 0.49 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | IDH2 | P48735 | 1/20 | 0.47 |
| ▸ | CDK7 | P50613 | 7/20 | 0.46 |
| ▸ | CCNH | P51946 | 6/20 | 0.46 |
| ▸ | MNAT1 | P51948 | 5/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17961788 | 0.89 | KDM4E (0.55) | KDM4EGAACCNKCDK12CCNT1 | |
| SCHEMBL17961781 | 0.89 | KDM4E (0.55) | KDM4EGAACCNKCDK12CCNT1 | |
| SCHEMBL17961784 | 0.89 | KDM4E (0.55) | KDM4EGAACCNKCDK12CCNT1 | |
| Hydrochloric Acid SCHEMBL4112492 | 0.87 | KDM4E (0.53) | KDM4EGAACCNKCDK12CCNT1 | |
| SCHEMBL30259523 | 0.86 | KDM4E (0.67) | KDM4EGAACCNKCDK12CCNT1 | |
| SCHEMBL268925 | 0.81 | CCNK (0.50) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL269583 | 0.81 | CCNK (0.50) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL17961872 | 0.81 | KDM4E (0.57) | KDM4EGAAMAPK1 | |
| SCHEMBL4705576 | 0.80 | IRAK4 (0.52) | PRKCZCDK7CCNHMAPK10 | |
| SCHEMBL13524818 | 0.80 | BRD4 (0.52) | CCNKCDK12CCNT1CDK9CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4295852-A2 | PIPERIDINE DERIVATIVES AS INHIBITORS OF CYCLIN DEPENDENT KINASE 7 (CDK7) | Syros Pharmaceuticals, Inc. (US) | 2023-12-27 | — | — | EP | disclosed |
| US-20230063457-A1 | DNA-PK INHIBITING COMPOUNDS | PROVINCIAL HEALTH SERVICES AUTHORITY (CA) | 2023-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230063457-A1 | DNA-PK INHIBITING COMPOUNDS | DCK, POLK, ERCC2 | KDM4E 760/4885GAA 484/4885CCNK 88/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.