Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | NPC1 | O15118 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 1.00 |
| ▸ | THRB | P10828 | 1/20 | 1.00 |
| ▸ | PKM | P14618 | 1/20 | 1.00 |
| ▸ | HPGD | P15428 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | STAT6 | P42226 | 1/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 1.00 |
| ▸ | RAB9A | P51151 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 1/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 1.00 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2681339 | 1.00 | CYP1A2 (1.00) | CYP1A2CYP3A4CYP2C9KDM4EMEN1 | |
| SCHEMBL8738492 | 0.81 | CYP1A2 (0.68) | CYP1A2CYP3A4CYP2C9KDM4EMEN1 | |
| SCHEMBL10735454 | 0.79 | KDM4E (0.65) | CYP1A2CYP3A4CYP2C9KDM4EMEN1 | |
| SCHEMBL4909545 | 0.75 | KDM4E (0.60) | CYP1A2CYP3A4CYP2C9KDM4EMEN1 | |
| SCHEMBL5250247 | 0.71 | HPGD (0.56) | CYP1A2CYP3A4CYP2C9KDM4EMEN1 | |
| SCHEMBL22955338 | 0.71 | CYP3A4 (0.55) | CYP1A2CYP3A4CYP2C9KDM4EMEN1 | |
| SCHEMBL4059653 | 0.71 | HTT (0.55) | CYP1A2CYP3A4CYP2C9KDM4EMEN1 | |
| SCHEMBL13607932 | 0.71 | KDM4E (0.55) | CYP1A2CYP3A4CYP2C9KDM4EMEN1 | |
| SCHEMBL1720364 | 0.71 | CYP1A2 (0.55) | CYP1A2CYP3A4CYP2C9KDM4EMEN1 | |
| SCHEMBL15756742 | 0.70 | KDM4E (0.54) | CYP1A2CYP3A4CYP2C9KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230044407-A1 | TARGETING MB2 OF THE MYC ONCOGENE AND ITS INTERACTION WITH TRRAP IN CANCER | THE TRUSTEES OF DARTMOUTH COLLEGE | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230044407-A1 | TARGETING MB2 OF THE MYC ONCOGENE AND ITS INTERACTION WITH TRRAP IN CANCER | MYCBP, MYC, TERF2IP | CYP1A2 4398/4885CYP3A4 4472/4885CYP2C9 4835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.