Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | STAT6 | P42226 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14493280 | 0.81 | NPBWR1 (0.46) | HPGDKDM4EALDH1A1HSD17B10MEN1 | |
| SCHEMBL5249728 | 0.77 | GAA (0.53) | HPGDKDM4EALDH1A1HSD17B10MEN1 | |
| SCHEMBL24347819 | 0.77 | NPBWR1 (0.61) | HPGDKDM4EALDH1A1HSD17B10MEN1 | |
| SCHEMBL5252061 | 0.72 | TNKS (0.53) | HPGDKDM4EALDH1A1HSD17B10MEN1 | |
| SCHEMBL2681339 | 0.71 | CYP1A2 (1.00) | HPGDKDM4EALDH1A1HSD17B10MEN1 | |
| SCHEMBL30260463 | 0.71 | CYP1A2 (1.00) | HPGDKDM4EALDH1A1HSD17B10MEN1 | |
| SCHEMBL5943243 | 0.69 | KDR (0.44) | HPGDKDM4EALDH1A1NPC1PKM | |
| SCHEMBL5252814 | 0.69 | KDM4E (0.61) | HPGDKDM4EALDH1A1HSD17B10MEN1 | |
| SCHEMBL5249576 | 0.68 | KDM4E (0.61) | HPGDKDM4EALDH1A1MEN1NPC1 | |
| SCHEMBL5250588 | 0.67 | GUSB (0.62) | ALDH1A1MEN1NPC1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373270-B1 | TRICYCLIC QUINOXALINE DERIVATIVES AS A UV FILTER | MERCK PATENT GMBH (DE) | 2007-06-06 | — | — | EP | disclosed |
| EP-1373270-B1 | TRICYCLIC QUINOXALINE DERIVATIVES AS A UV FILTER | MERCK PATENT GMBH (DE) | 2007-06-06 | — | — | EP | disclosed |
| US-20060222607-A1 | Tricyclic quinoxaline and quinoline derivatives as UV filters | PFLUCKER FRANK | 2006-10-05 | — | — | US | disclosed |
| US-7101537-B2 | Tricyclic quinoxaline and quinoline derivatives as a UV filter | MERCK PATENTGESELLSCHAFT (DE) | 2006-09-05 | — | — | US | disclosed |
| US-20040102446-A1 | Tricyclic quinoxaline derivatives as a uv filter | MERCK PATENT GMBH (DE) | 2004-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102446-A1 | Tricyclic quinoxaline derivatives as a uv filter | CUTA, CYP1B1, TPH1 | HPGD 237/4885KDM4E 1646/4885ALDH1A1 289/4885 |
| US-20060222607-A1 | Tricyclic quinoxaline and quinoline derivatives as UV filters | RECQL, CUTA, NQO2 | HPGD 231/4885KDM4E 1602/4885ALDH1A1 682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.