Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.85 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.85 |
| ▸ | MEN1 | O00255 | 5/20 | 0.85 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.85 |
| ▸ | LMNA | P02545 | 5/20 | 0.85 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.85 |
| ▸ | GAA | P10253 | 2/20 | 0.85 |
| ▸ | UBE2N | P61088 | 2/20 | 0.85 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.85 |
| ▸ | HTT | P42858 | 5/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.79 |
| ▸ | POLB | P06746 | 1/20 | 0.79 |
| ▸ | THRB | P10828 | 1/20 | 0.79 |
| ▸ | ATM | Q13315 | 1/20 | 0.79 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.76 |
| ▸ | CA11 | O75493 | 1/20 | 0.72 |
| ▸ | CA1 | P00915 | 1/20 | 0.72 |
| ▸ | CA2 | P00918 | 1/20 | 0.72 |
| ▸ | CA9 | Q16790 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30260542 | 0.86 | MAPT (1.00) | MAPTTDP1MEN1KMT2ALMNA | |
| SCHEMBL30260628 | 0.83 | FAAH (0.74) | MAPTTDP1MEN1KMT2ALMNA | |
| SCHEMBL23483662 | 0.83 | FAAH (0.74) | MAPTTDP1MEN1KMT2ALMNA | |
| SCHEMBL30260530 | 0.82 | MAPT (0.70) | MAPTTDP1MEN1KMT2ALMNA | |
| SCHEMBL29562326 | 0.78 | MAPT (1.00) | MAPTTDP1MEN1KMT2ALMNA | |
| SCHEMBL30260455 | 0.77 | MAPT (0.86) | MAPTTDP1MEN1KMT2ALMNA | |
| SCHEMBL23483677 | 0.74 | MAPT (0.67) | MAPTTDP1MEN1KMT2ALMNA | |
| SCHEMBL30260471 | 0.74 | MAPT (0.67) | MAPTTDP1MEN1KMT2ALMNA | |
| SCHEMBL23483898 | 0.72 | KMT2A (1.00) | MAPTMEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL30260525 | 0.72 | KMT2A (1.00) | MAPTMEN1KMT2ALMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230044407-A1 | TARGETING MB2 OF THE MYC ONCOGENE AND ITS INTERACTION WITH TRRAP IN CANCER | THE TRUSTEES OF DARTMOUTH COLLEGE | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230044407-A1 | TARGETING MB2 OF THE MYC ONCOGENE AND ITS INTERACTION WITH TRRAP IN CANCER | MYCBP, MYC, TERF2IP | MAPT 3232/4885TDP1 1966/4885MEN1 2382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.