Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 14/20 | 0.78 |
| ▸ | CDK12 | Q9NYV4 | 14/20 | 0.78 |
| ▸ | CCNT1 | O60563 | 13/20 | 0.78 |
| ▸ | CDK9 | P50750 | 13/20 | 0.78 |
| ▸ | CCNE1 | P24864 | 11/20 | 0.78 |
| ▸ | CDK2 | P24941 | 11/20 | 0.78 |
| ▸ | CDK7 | P50613 | 13/20 | 0.70 |
| ▸ | CCNH | P51946 | 12/20 | 0.70 |
| ▸ | MNAT1 | P51948 | 11/20 | 0.70 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24839845 | 0.97 | CCNK (0.83) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL21549428 | 0.90 | CCNK (0.66) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL24839784 | 0.88 | CCNK (1.00) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL30260874 | 0.83 | CCNK (0.94) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL17150599 | 0.83 | CCNT1 (0.60) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL24839833 | 0.83 | CCNK (1.00) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL24839792 | 0.83 | CDK7 (1.00) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL20190945 | 0.83 | CCNT1 (1.00) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL24839342 | 0.83 | CCNT1 (1.00) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL29613489 | 0.83 | CCNT1 (1.00) | CCNKCDK12CCNT1CDK9CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023040998-A1 | A CYCLIN-DEPENDENT KINASE INHIBITOR | Taizhou Eoc Pharma Co., Ltd. (CN) | 2023-03-23 | — | — | WO | disclosed |