Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 16/20 | 0.40 |
| ▸ | CDK12 | Q9NYV4 | 16/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 16/20 | 0.40 |
| ▸ | CDK2 | P24941 | 16/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 15/20 | 0.40 |
| ▸ | CDK9 | P50750 | 15/20 | 0.40 |
| ▸ | CDK7 | P50613 | 8/20 | 0.38 |
| ▸ | CCNH | P51946 | 8/20 | 0.38 |
| ▸ | MNAT1 | P51948 | 5/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25363465 | 0.91 | CCNE1 (0.41) | CCNKCDK12CCNE1CDK2CCNT1 | |
| SCHEMBL31122437 | 0.91 | CCNE1 (0.41) | CCNKCDK12CCNE1CDK2CCNT1 | |
| SCHEMBL26043873 | 0.87 | CCNE1 (0.39) | CCNKCDK12CCNE1CDK2CCNT1 | |
| SCHEMBL30456148 | 0.86 | CCNK (0.44) | CCNKCDK12CCNE1CDK2CCNT1 | |
| SCHEMBL25362594 | 0.86 | CCNK (0.44) | CCNKCDK12CCNE1CDK2CCNT1 | |
| SCHEMBL25583407 | 0.85 | CCNK (0.37) | CCNKCDK12CCNE1CDK2CCNT1 | |
| SCHEMBL25597490 | 0.83 | CCNK (0.36) | CCNKCDK12CCNE1CDK2CCNT1 | |
| SCHEMBL24588169 | 0.83 | CCNT1 (0.39) | CCNKCDK12CCNE1CDK2CCNT1 | |
| SCHEMBL29699056 | 0.83 | CCNT1 (0.39) | CCNKCDK12CCNE1CDK2CCNT1 | |
| SCHEMBL25597105 | 0.81 | KDM4E (0.45) | CCNKCDK12CCNE1CDK2CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023040998-A1 | A CYCLIN-DEPENDENT KINASE INHIBITOR | Taizhou Eoc Pharma Co., Ltd. (CN) | 2023-03-23 | — | — | WO | disclosed |