SCHEMBL26043873 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	CCNE1	P24864	16/20	0.39

▸	CDK2	P24941	16/20	0.39

▸	CCNK	O75909	16/20	0.39

▸	CDK12	Q9NYV4	16/20	0.39

▸	CCNT1	O60563	15/20	0.39

▸	CDK9	P50750	15/20	0.39

▸	CDK7	P50613	8/20	0.35

▸	CCNH	P51946	8/20	0.35

▸	MNAT1	P51948	5/20	0.35

▸	NR4A2	P43354	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL26043875	0.90	CCNE1 (0.39)	CCNE1CDK2CCNKCDK12CCNT1
SCHEMBL31122437	0.89	CCNE1 (0.41)	CCNE1CDK2CCNKCDK12CCNT1
SCHEMBL25363465	0.89	CCNE1 (0.41)	CCNE1CDK2CCNKCDK12CCNT1
SCHEMBL30260889	0.87	CCNK (0.40)	CCNE1CDK2CCNKCDK12CCNT1
SCHEMBL30456148	0.84	CCNK (0.44)	CCNE1CDK2CCNKCDK12CCNT1
SCHEMBL25362594	0.84	CCNK (0.44)	CCNE1CDK2CCNKCDK12CCNT1
SCHEMBL25597105	0.79	KDM4E (0.45)	CCNE1CDK2CCNKCDK12CCNT1
SCHEMBL25597137	0.79	CCNK (0.40)	CCNE1CDK2CCNKCDK12CCNT1
SCHEMBL21178282	0.77	CCNK (0.51)	CCNE1CDK2CCNKCDK12CCNT1
SCHEMBL30260968	0.77	CCNK (0.51)	CCNE1CDK2CCNKCDK12CCNT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023116761-A1	PYRIMIDINE HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE	英矽智能科技知识产权有限公司	2023-06-29	—	—	WO	disclosed