Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.83 |
| ▸ | ARG2 | P78540 | 4/20 | 0.52 |
| ▸ | ARG1 | P05089 | 3/20 | 0.52 |
| ▸ | NOS2 | P35228 | 6/20 | 0.50 |
| ▸ | NOS1 | P29475 | 4/20 | 0.50 |
| ▸ | NOS3 | P29474 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL6538526 | 1.00 | GSR (0.83) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL15753994 | 1.00 | GSR (0.83) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL19742881 | 1.00 | GSR (0.83) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL1433568 | 1.00 | GSR (0.83) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL5581427 | 1.00 | GSR (0.83) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL301792 | 1.00 | GSR (0.83) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL28318609 | 1.00 | GSR (0.83) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL1696587 | 1.00 | GSR (0.83) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL7861429 | 1.00 | GSR (0.83) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL9448118 | 0.98 | GSR (0.80) | GSRARG2ARG1NOS2NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 301 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023172648-A2 | FLUOROGENIC SUBSTRATES FOR AMINOPEPTIDASE DETECTION IN BIOFLUIDS | GLYMPSE BIO, INC. (US) | 2023-09-14 | — | — | WO | claimed |
| WO-2023140197-A1 | MODIFIED RECOMBINANT ADENO-ASSOCIATED VIRUS (AAV)-BINDING PROTEIN AND METHOD OF ANALYSIS OF AAV BASED ON INFECTION ABILITY | 東ソー株式会社 | 2023-07-27 | — | — | WO | claimed |
| CN-115990265-A | Polymer-drug conjugate capable of targeting tumor cell endoplasmic reticulum | 四川大学 | 2023-04-21 | — | — | CN | claimed |
| CN-113195487-A | 2, 3-diaminosuccinyl conjugate linkers | 杭州多禧生物科技有限公司 | 2021-07-30 | — | — | CN | claimed |
| EP-3818062-A1 | CROSS-LINKED PYRROLOBENZODIAZEPINE DIMER (PBD) DERIVATIVE AND ITS CONJUGATES | Hangzhou Dac Biotech Co., Ltd (CN) | 2021-05-12 | — | — | EP | claimed |
| CN-112272669-A | Cross-linked pyrrolobenzodiazepine dimer (PBD) derivatives and conjugates thereof | 杭州多禧生物科技有限公司 | 2021-01-26 | — | — | CN | claimed |
| EP-3606922-A1 | CONJUGATION OF A CYTOTOXIC DRUG WITH BIS-LINKAGE | Hangzhou Dac Biotech Co., Ltd (CN) | 2020-02-12 | — | — | EP | claimed |
| WO-2020006722-A1 | CROSS-LINKED PYRROLOBENZODIAZEPINE DIMER (PBD) DERIVATIVE AND ITS CONJUGATES | HANGZHOU DAC BIOTECH CO., LTD (CN) | 2020-01-09 | — | — | WO | claimed |
| CN-110621673-A | Double-stranded linked cytotoxic drug conjugates | 杭州多禧生物科技有限公司 | 2019-12-27 | — | — | CN | claimed |
| WO-2018185526-A1 | CONJUGATION OF A CYTOTOXIC DRUG WITH BIS-LINKAGE | HANGZHOU DAC BIOTECH CO., LTD (CN) | 2018-10-11 | — | — | WO | claimed |
| EP-1907843-B1 | UNIFORMLY CONJUGATED SERINE HYDROLASES | ISRAEL STATE (IL) | 2013-11-27 | — | — | EP | claimed |
| WO-2013077886-A2 | PROTEASE DEGRADABLE POLYPEPTIDES AND USES THEREOF | THE METHODIST HOSPITAL SYSTEM (US) | 2013-05-30 | — | — | WO | claimed |
| US-8227251-B2 | Mass spectrum-based identification and quantitation of proteins and peptides | INSTITUTE FOR SYSTEMS BIOLOGY (US) | 2012-07-24 | — | — | US | claimed |
| WO-2012004380-A1 | DIAGNOSIS, PROPHYLAXIS AND THERAPY OF ALZHEIMER'S DISEASE AND OTHER NEURODEMENTING DISORDERS | BALAKRISHNAN KARTHIKEYAN (DE) | 2012-01-12 | — | — | WO | claimed |
| EP-2404612-A1 | Diagnosis, prophylaxis and therapy of Alzheimer's disease and other neurodementing disorders | Balakrishnan, Karthikeyan (DE) | 2012-01-11 | — | — | EP | claimed |
| WO-2010120946-A1 | IMPROVEMENTS IN MASS SPECTRUM-BASED IDENTIFICATION AND QUANTITATION OF PROTEINS AND PEPTIDES | INSTITUTE FOR SYSTEMS BIOLOGY (US) | 2010-10-21 | — | — | WO | claimed |
| US-20100261279-A1 | MASS SPECTRUM-BASED IDENTIFICATION AND QUANTITATION OF PROTEINS AND PEPTIDES | INSTITUTE FOR SYSTEMS BIOLOGY | 2010-10-14 | — | — | US | claimed |
| EP-1944314-A1 | Diagnosis of Alzheimer's disease and other neurodementing disorders | Philipps-Universität Marburg (DE) | 2008-07-16 | — | — | EP | claimed |
| WO-2026077418-A9 | ISOINDOLINE COMPOUND CONTAINING PHENYLETHOXYALKYLENEAMINE STRUCTURE, CONJUGATE THEREOF, AND USE THEREOF | 上海海雁医药科技有限公司 | 2026-05-15 | — | — | WO | disclosed |
| EP-0069678-A2 | 3-Fucosyl-N-acetyl-lactosamine derivatives, their preparation and their biological applications | CHOAY S.A. (FR) | 1983-01-12 | — | — | EP | disclosed |