Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 20/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.44 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16770853 | 0.89 | SCN9A (0.43) | SCN9ASCN5A | |
| SCHEMBL16759010 | 0.87 | SCN9A (0.41) | SCN9ASCN5A | |
| SCHEMBL16759604 | 0.86 | SCN9A (0.42) | SCN9ASCN5A | |
| SCHEMBL16448627 | 0.82 | SCN9A (0.66) | SCN9ASCN5A | |
| SCHEMBL15558549 | 0.82 | SCN9A (0.64) | SCN9ASCN5A | |
| SCHEMBL16448611 | 0.81 | SCN9A (0.60) | SCN9ASCN5ASCN1ASCN2ASCN8A | |
| SCHEMBL16448723 | 0.81 | SCN9A (0.65) | SCN9ASCN5A | |
| SCHEMBL15557587 | 0.81 | SCN9A (0.65) | SCN9ASCN5A | |
| SCHEMBL30261612 | 0.81 | SCN7A (0.47) | SCN9ASCN5A | |
| SCHEMBL16770388 | 0.81 | SCN9A (0.50) | SCN9ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023028077-A1 | SODIUM CHANNEL INHIBITORS AND METHODS OF DESIGNING SAME | GENENTECH, INC. (US) | 2023-03-02 | — | — | WO | disclosed |