Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN7A | Q01118 | 4/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 13/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL662496 | 0.85 | NPC1 (0.46) | MRGPRX4NPC1 | |
| SCHEMBL17423083 | 0.83 | SCN7A (0.51) | SCN7AMRGPRX4SCN9ASCN5APTGDR2 | |
| SCHEMBL16759678 | 0.83 | SCN7A (0.70) | SCN7ASCN9ASCN5A | |
| SCHEMBL17061721 | 0.83 | SCN9A (0.48) | SCN7ASCN9ASCN5APTGDR2 | |
| SCHEMBL16771119 | 0.82 | SCN7A (0.48) | SCN7ASCN9ASCN5A | |
| SCHEMBL16770998 | 0.82 | SCN7A (0.48) | SCN7ASCN9ASCN5A | |
| SCHEMBL16771113 | 0.81 | SCN7A (0.48) | SCN7ASCN9ASCN5A | |
| SCHEMBL30261496 | 0.81 | SCN9A (0.44) | SCN9ASCN5A | |
| SCHEMBL23861709 | 0.80 | SCN7A (0.45) | SCN7AMRGPRX4SCN9ASCN5APTGDR2 | |
| SCHEMBL18571084 | 0.80 | SCN7A (0.46) | SCN7AMRGPRX4SCN9ASCN5APTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023028077-A1 | SODIUM CHANNEL INHIBITORS AND METHODS OF DESIGNING SAME | GENENTECH, INC. (US) | 2023-03-02 | — | — | WO | disclosed |