Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 13/20 | 0.39 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | CTSD | P07339 | 2/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30008256 | 0.93 | BACE1 (0.39) | BACE1CTSDMMESLC6A2BACE2 | |
| SCHEMBL30390358 | 0.92 | CD274 (0.41) | BACE1PDCD1LG2CD274CTSDMME | |
| SCHEMBL29986038 | 0.92 | PDCD1LG2 (0.39) | BACE1PDCD1LG2CD274CTSDECE1 | |
| SCHEMBL31391114 | 0.92 | SLC6A2 (0.36) | BACE1MMESLC6A2BACE2 | |
| SCHEMBL29383357 | 0.90 | ECE1 (0.34) | MMEECE1 | |
| SCHEMBL30645271 | 0.90 | PDCD1LG2 (0.38) | BACE1PDCD1LG2CD274MMESLC6A2 | |
| SCHEMBL29559148 | 0.89 | FNTA (0.40) | MMEECE1 | |
| SCHEMBL30020949 | 0.88 | BACE1 (0.49) | BACE1CTSDBACE2 | |
| SCHEMBL31474495 | 0.88 | BACE1 (0.33) | BACE1MMEECE1 | |
| SCHEMBL31514360 | 0.88 | PDCD1LG2 (0.37) | BACE1PDCD1LG2CD274MMESLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230040544-A1 | COMPOSITIONS AND METHODS FOR RESTORING AND MAINTAINING THE DYSTROPHIN-ASSOCIATED PROTEIN COMPLEX (DAPC) | SAREPTA THERAPEUTICS, INC. | 2023-02-09 | — | — | US | disclosed |