Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 17/20 | 0.49 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 3/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31596910 | 0.93 | BACE1 (0.47) | BACE1BACE2OPRD1CTSD | |
| SCHEMBL30640025 | 0.92 | BACE1 (0.48) | BACE1BACE2CTSD | |
| SCHEMBL30873786 | 0.92 | BACE1 (0.48) | BACE1BACE2CTSD | |
| SCHEMBL30567747 | 0.90 | BACE1 (0.46) | BACE1OPRD1CTSD | |
| SCHEMBL28964063 | 0.90 | BACE1 (0.59) | BACE1BACE2CTSD | |
| SCHEMBL30637767 | 0.90 | BACE1 (0.59) | BACE1BACE2CTSD | |
| SCHEMBL29421174 | 0.89 | BACE1 (0.37) | BACE1OPRD1CTSD | |
| SCHEMBL31420013 | 0.89 | BACE1 (0.45) | BACE1BACE2CTSDCASP3CASP7 | |
| SCHEMBL30512755 | 0.89 | BACE1 (0.42) | BACE1 | |
| SCHEMBL30261968 | 0.88 | BACE1 (0.39) | BACE1BACE2CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220378933-A1 | IL-2 COMPOSITIONS AND METHODS OF USE THEREOF | PROVIVA THERAPEUTICS (HONG KONG) LIMITED (CN) | 2022-12-01 | — | — | US | disclosed |