SCHEMBL30262006

CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](NC(=O)CN)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	GLP1R	P43220	11/20	0.52

▸	CALCR	P30988	4/20	0.51

▸	CRHR1	P34998	1/20	0.51

▸	CRHR2	Q13324	1/20	0.51

▸	RXFP1	Q9HBX9	1/20	0.51

▸	HCRTR1	O43613	1/20	0.50

▸	HCRTR2	O43614	1/20	0.50

▸	GRIN2D	O15399	1/20	0.49

▸	GRIN3B	O60391	1/20	0.49

▸	GRIN1	Q05586	1/20	0.49

▸	GRIN2A	Q12879	1/20	0.49

▸	GRIN2B	Q13224	1/20	0.49

▸	GRIN2C	Q14957	1/20	0.49

▸	GRIN3A	Q8TCU5	1/20	0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29625325	0.96	CALCR (0.55)	GLP1RCALCRCRHR1CRHR2GRIN2D
SCHEMBL30524353	0.91	GLP1R (0.48)	GLP1RCALCRRXFP1HCRTR1HCRTR2
SCHEMBL30524358	0.89	GLP1R (0.62)	GLP1RCALCRCRHR1CRHR2
SCHEMBL29796964	0.89	GLP1R (0.55)	GLP1RCALCRCRHR1CRHR2
Magainin I SCHEMBL29392863	0.89	CALCR (0.59)	GLP1RCALCRCRHR1CRHR2RXFP1
SCHEMBL29633610	0.88	CALCR (0.63)	GLP1RCALCRCRHR1CRHR2RXFP1
Magainin 2 SCHEMBL29357968	0.88	CALCR (0.63)	GLP1RCALCRCRHR1CRHR2RXFP1
SCHEMBL29797050	0.88	GLP1R (0.53)	GLP1RCALCRCRHR1CRHR2
SCHEMBL30436811	0.87	GLP1R (0.56)	GLP1RCALCRCRHR1CRHR2
SCHEMBL30525424	0.87	GRPR (0.47)	GLP1RCALCRCRHR1CRHR2HCRTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20230040544-A1	COMPOSITIONS AND METHODS FOR RESTORING AND MAINTAINING THE DYSTROPHIN-ASSOCIATED PROTEIN COMPLEX (DAPC)	SAREPTA THERAPEUTICS, INC.	2023-02-09	—	—	US	disclosed