Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 20/20 | 0.71 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.54 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.54 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.54 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30261967 | 0.95 | FGFR4 (0.73) | FGFR4FGFR2 | |
| SCHEMBL30261992 | 0.86 | FGFR4 (0.73) | FGFR4CYP2C8FGFR1CYP2C9CYP2B6 | |
| SCHEMBL30261973 | 0.86 | FGFR4 (0.73) | FGFR4CYP2C8FGFR1CYP2C9CYP2B6 | |
| SCHEMBL30262069 | 0.86 | FGFR4 (0.73) | FGFR4CYP2C8FGFR1CYP2C9CYP2B6 | |
| SCHEMBL30261979 | 0.84 | FGFR4 (0.86) | FGFR4FGFR2 | |
| SCHEMBL24224980 | 0.83 | FGFR4 (1.00) | FGFR4 | |
| SCHEMBL16072040 | 0.83 | FGFR4 (1.00) | FGFR4 | |
| SCHEMBL30262041 | 0.83 | FGFR4 (0.74) | FGFR4CYP2C8FGFR1CYP2C9CYP2B6 | |
| SCHEMBL23629706 | 0.82 | FGFR4 (0.71) | FGFR4CYP2C8FGFR1CYP2C9CYP2B6 | |
| SCHEMBL30800702 | 0.82 | FGFR4 (0.71) | FGFR4CYP2C8FGFR1CYP2C9CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023039828-A1 | FUSED RING COMPOUNDS AS INHIBITORS OF FGFR4 TYROSINE KINASES | NUTSHELL BIOTECH (SHANGHAI) CO., LTD. (CN) | 2023-03-23 | — | — | WO | disclosed |