SCHEMBL30262133

CC[C@H](C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H](N)CC(C)C)C(C)C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCCCN)C(=O)O)C(C)C)[C@@H](C)CC)[C@@H](C)O

nearest known ligand 0.54

Predicted protein targets (top 4)

	gene	UniProt	supporting neighbours	confidence
▸	CALCR	P30988	4/20	0.54

▸	GLP1R	P43220	15/20	0.53

▸	CRHR1	P34998	1/20	0.52

▸	CRHR2	Q13324	1/20	0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30524358	0.92	GLP1R (0.62)	CALCRGLP1RCRHR1CRHR2
SCHEMBL31307289	0.91	GLP1R (0.60)	GLP1R
SCHEMBL29967394	0.88	GLP1R (0.65)	CALCRGLP1RCRHR1CRHR2
SCHEMBL30432055	0.88	CALCR (0.59)	CALCRGLP1RCRHR1CRHR2
SCHEMBL29827711	0.88	CRHR1 (0.55)	CALCRGLP1RCRHR1CRHR2
SCHEMBL29796964	0.88	GLP1R (0.55)	CALCRGLP1RCRHR1CRHR2
SCHEMBL30658361	0.88	CALCR (0.63)	CALCRGLP1RCRHR1CRHR2
SCHEMBL31410890	0.87	GLP1R (0.58)	GLP1R
SCHEMBL31548691	0.87	GLP1R (0.48)	CALCRGLP1RCRHR1CRHR2
SCHEMBL31182926	0.87	CRHR1 (0.54)	CALCRGLP1RCRHR1CRHR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20230040544-A1	COMPOSITIONS AND METHODS FOR RESTORING AND MAINTAINING THE DYSTROPHIN-ASSOCIATED PROTEIN COMPLEX (DAPC)	SAREPTA THERAPEUTICS, INC.	2023-02-09	—	—	US	disclosed