SCHEMBL30262200

CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CC(=O)O)C(C)C)[C@@H](C)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	GLP1R	P43220	9/20	0.60

▸	GCGR	P47871	9/20	0.60

▸	CALCR	P30988	4/20	0.59

▸	C5AR1	P21730	1/20	0.57

▸	GIPR	P48546	6/20	0.56

▸	APLNR	P35414	1/20	0.56

▸	CRHR1	P34998	1/20	0.56

▸	CRHR2	Q13324	1/20	0.56

▸	NPY2R	P49146	1/20	0.56

▸	NPY4R	P50391	1/20	0.56

▸	NPY5R	Q15761	1/20	0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30262218	0.92	C5AR1 (0.59)	GLP1RGCGRCALCRC5AR1GIPR
SCHEMBL30432646	0.89	CALCR (0.67)	CALCRC5AR1NPY2RNPY4RNPY5R
SCHEMBL31295720	0.88	CALCR (0.65)	GLP1RGCGRCALCRAPLNRCRHR1
SCHEMBL31182722	0.88	GLP1R (0.62)	GLP1RGCGRCALCRGIPRNPY2R
SCHEMBL30903277	0.88	C5AR1 (0.65)	GLP1RGCGRCALCRC5AR1APLNR
SCHEMBL30436896	0.88	CALCR (0.68)	GLP1RGCGRCALCRC5AR1NPY2R
SCHEMBL30511759	0.88	CALCR (0.66)	GLP1RGCGRCALCRC5AR1NPY2R
SCHEMBL31182477	0.88	APLNR (0.64)	C5AR1APLNRNPY2RNPY4RNPY5R
SCHEMBL30859188	0.88	CALCR (0.63)	GLP1RGCGRCALCRC5AR1GIPR
SCHEMBL30495793	0.88	CALCR (0.67)	GLP1RGCGRCALCRC5AR1CRHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20230040544-A1	COMPOSITIONS AND METHODS FOR RESTORING AND MAINTAINING THE DYSTROPHIN-ASSOCIATED PROTEIN COMPLEX (DAPC)	SAREPTA THERAPEUTICS, INC.	2023-02-09	—	—	US	disclosed