Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.64 |
| ▸ | DNM2 | P50570 | 8/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29156884 | 1.00 | TLR8 (0.64) | TLR8DNM2TLR7CYP2D6CYP2C19 | |
| SCHEMBL20434279 | 0.93 | TLR8 (0.73) | TLR8TLR7CYP2D6CYP2C19HRH4 | |
| SCHEMBL5791298 | 0.85 | TLR8 (0.88) | TLR8DNM2TLR7CYP2D6 | |
| SCHEMBL16703349 | 0.84 | CYP2D6 (0.62) | TLR8DNM2CYP2D6CYP2C19HRH4 | |
| SCHEMBL7124897 | 0.84 | CYP2D6 (0.62) | TLR8DNM2CYP2D6CYP2C19HRH4 | |
| SCHEMBL7117794 | 0.84 | CYP2D6 (0.62) | TLR8DNM2CYP2D6CYP2C19HRH4 | |
| SCHEMBL7135338 | 0.84 | CYP2D6 (0.62) | TLR8DNM2CYP2D6CYP2C19HRH4 | |
| SCHEMBL7118699 | 0.84 | CYP2D6 (0.62) | TLR8DNM2CYP2D6CYP2C19HRH4 | |
| SCHEMBL25086837 | 0.83 | CYP2D6 (0.53) | TLR8TLR7CYP2D6CYP2C19HRH4 | |
| SCHEMBL2849398 | 0.83 | TLR8 (0.90) | TLR8DNM2TLR7CYP2D6HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161534-B1 | POLYMERS, COMPOSITIONS AND METHODS FOR TREATING HYPERURICEMIA | WATERSTONE PHARMACEUTICALS WUHAN CO LTD (CN) | 2024-11-06 | — | — | EP | claimed |
| EP-4164659-B1 | POLYMERS, COMPOSITIONS AND METHODS FOR TREATING HYPERURICEMIA | WATERSTONE PHARMACEUTICALS WUHAN CO LTD (CN) | 2024-03-27 | — | — | EP | claimed |
| CN-116018147-A | Polymers, compositions and methods for treating hyperuricemia | 中美华世通生物医药科技(武汉)股份有限公司 | 2023-04-25 | — | — | CN | claimed |
| CN-116018146-A | Polymers, compositions and methods for treating hyperuricemia | 中美华世通生物医药科技(武汉)股份有限公司 | 2023-04-25 | — | — | CN | claimed |
| EP-4164659-A1 | POLYMERS, COMPOSITIONS AND METHODS FOR TREATING HYPERURICEMIA | Waterstone Pharmaceuticals (Wuhan) Co., Ltd. (CN) | 2023-04-19 | — | — | EP | claimed |
| EP-4161534-A1 | POLYMERS, COMPOSITIONS AND METHODS FOR TREATING HYPERURICEMIA | Waterstone Pharmaceuticals (Wuhan) Co., Ltd. (CN) | 2023-04-12 | — | — | EP | claimed |
| WO-2023023939-A1 | POLYMERS, COMPOSITIONS AND METHODS FOR TREATING HYPERURICEMIA | WATERSTONE PHARMACEUTICALS (WUHAN) CO., LTD. (CN) | 2023-03-02 | — | — | WO | claimed |
| WO-2023023938-A1 | POLYMERS, COMPOSITIONS AND METHODS FOR TREATING HYPERURICEMIA | WATERSTONE PHARMACEUTICALS (WUHAN) CO., LTD. (CN) | 2023-03-02 | — | — | WO | claimed |
| CN-116018147-A | Polymers, compositions and methods for treating hyperuricemia | 中美华世通生物医药科技(武汉)股份有限公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-116018146-A | Polymers, compositions and methods for treating hyperuricemia | 中美华世通生物医药科技(武汉)股份有限公司 | 2023-04-25 | — | — | CN | disclosed |
| EP-4164659-A1 | POLYMERS, COMPOSITIONS AND METHODS FOR TREATING HYPERURICEMIA | Waterstone Pharmaceuticals (Wuhan) Co., Ltd. (CN) | 2023-04-19 | — | — | EP | disclosed |
| EP-4161534-A1 | POLYMERS, COMPOSITIONS AND METHODS FOR TREATING HYPERURICEMIA | Waterstone Pharmaceuticals (Wuhan) Co., Ltd. (CN) | 2023-04-12 | — | — | EP | disclosed |
| WO-2023023939-A1 | POLYMERS, COMPOSITIONS AND METHODS FOR TREATING HYPERURICEMIA | WATERSTONE PHARMACEUTICALS (WUHAN) CO., LTD. (CN) | 2023-03-02 | — | — | WO | disclosed |
| WO-2023023938-A1 | POLYMERS, COMPOSITIONS AND METHODS FOR TREATING HYPERURICEMIA | WATERSTONE PHARMACEUTICALS (WUHAN) CO., LTD. (CN) | 2023-03-02 | — | — | WO | disclosed |