Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.60 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | DNM2 | P50570 | 8/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16703349 | 1.00 | CYP2D6 (0.62) | CYP2D6CYP2C19TLR8HRH4ALDH1A1 | |
| SCHEMBL7117794 | 1.00 | CYP2D6 (0.62) | CYP2D6CYP2C19TLR8HRH4ALDH1A1 | |
| SCHEMBL7135338 | 1.00 | CYP2D6 (0.62) | CYP2D6CYP2C19TLR8HRH4ALDH1A1 | |
| SCHEMBL7118699 | 1.00 | CYP2D6 (0.62) | CYP2D6CYP2C19TLR8HRH4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11755133 | 0.98 | CYP2D6 (0.60) | CYP2D6CYP2C19TLR8HRH4ALDH1A1 | |
| SCHEMBL11752857 | 0.98 | CYP2D6 (0.64) | CYP2D6CYP2C19TLR8HRH4ALDH1A1 | |
| SCHEMBL8600881 | 0.94 | TLR8 (0.69) | CYP2D6CYP2C19TLR8HRH4ALDH1A1 | |
| SCHEMBL8597545 | 0.87 | CYP2D6 (0.70) | CYP2D6CYP2C19TLR8HRH4ALDH1A1 | |
| SCHEMBL30263108 | 0.84 | TLR8 (0.64) | CYP2D6CYP2C19TLR8HRH4DNM2 | |
| SCHEMBL29156884 | 0.84 | TLR8 (0.64) | CYP2D6CYP2C19TLR8HRH4DNM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6511659-B2 | Treatment of alopecia, cosmetics | SOCIETE L'OREAL S.A. (FR) | 2003-01-28 | — | — | US | claimed |
| US-4025515-A | HERBICIDES | SANDOZ LTD. (CH) | 1977-05-24 | — | — | US | claimed |
| US-6653317-B2 | Pyrimidine 3-oxide compounds for inducing/stimulating hair growth and/or retarding hair loss | SOCIETE L'OREAL S.A. (FR) | 2003-11-25 | — | — | US | disclosed |
| US-20030130294-A1 | Pyrimidine 3-oxide compounds for inducing/stimulating hair growth and/or retarding hair loss | MAHE YANN (FR) | 2003-07-10 | — | — | US | disclosed |
| US-6511659-B2 | Treatment of alopecia, cosmetics | SOCIETE L'OREAL S.A. (FR) | 2003-01-28 | — | — | US | disclosed |
| US-20010044444-A1 | Pyrimidine 3-oxide compounds for inducing/stimulating hair growth and/or retarding hair loss | MAHE YANN (FR) | 2001-11-22 | — | — | US | disclosed |
| US-6291468-B1 | Pyrimidine 3-oxide compounds for inducing/stimulating hair growth and/or retarding hair loss | SOCIETE L'OREAL S.A. (FR) | 2001-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130294-A1 | Pyrimidine 3-oxide compounds for inducing/stimulating hair growth and/or retarding hair loss | TK2, TYR, MTR | CYP2D6 1449/4885CYP2C19 1927/4885TLR8 3325/4885 |
| US-20010044444-A1 | Pyrimidine 3-oxide compounds for inducing/stimulating hair growth and/or retarding hair loss | TK2, TYR, MTR | CYP2D6 1377/4885CYP2C19 1902/4885TLR8 3364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.