Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 7/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.57 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.57 |
| ▸ | PRKDC | P78527 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12316369 | 1.00 | HIF1A (0.62) | HIF1AMAPTALDH1A1KDM4EHTT | |
| SCHEMBL1644930 | 0.89 | MAPT (0.57) | HIF1AMAPTALDH1A1KDM4EHTT | |
| SCHEMBL4839678 | 0.87 | HIF1A (0.63) | HIF1AMAPTALDH1A1KDM4EHTT | |
| SCHEMBL26604551 | 0.87 | PRKDC (0.58) | HIF1AMAPTALDH1A1KDM4EHTT | |
| SCHEMBL20976848 | 0.87 | HIF1A (0.60) | HIF1AMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL4989973 | 0.86 | HIF1A (0.65) | HIF1AMAPTALDH1A1KDM4EHTT | |
| SCHEMBL16055881 | 0.86 | HIF1A (0.60) | HIF1AMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL1931343 | 0.85 | HIF1A (0.58) | HIF1AMAPTALDH1A1KDM4EHTT | |
| SCHEMBL1334225 | 0.84 | SIRT6 (0.61) | HIF1AMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL15547618 | 0.84 | PRKDC (0.56) | HIF1AMAPTALDH1A1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161921-A1 | COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF | Anima Biotech Inc. (US) | 2023-04-12 | — | — | EP | disclosed |