Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24107461 | 1.00 | MAPT (0.41) | MAPTKDM4EMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL30263377 | 0.91 | MAPT (0.43) | MAPTKDM4EMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL24107437 | 0.91 | MAPT (0.43) | MAPTKDM4EMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL24107566 | 0.89 | MAPT (0.40) | MAPTKDM4EMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL24107728 | 0.89 | RORC (0.42) | MAPTKDM4EMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL24107681 | 0.89 | ROCK1 (0.43) | MAPTKDM4EMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL24107680 | 0.89 | MAPT (0.42) | MAPTKDM4EMAPK1SMN1; SMN2MEN1 | |
| SCHEMBL24107715 | 0.88 | MAPT (0.39) | MAPTKDM4EMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL24107689 | 0.88 | MAPT (0.42) | MAPTKDM4EMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL24107462 | 0.87 | MAPT (0.42) | MAPTKDM4EMAPK1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161921-A1 | COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF | Anima Biotech Inc. (US) | 2023-04-12 | — | — | EP | disclosed |
| CN-115916776-A | Collagen 1 translation inhibitors and methods of use thereof | 艾尼莫生物科技公司 | 2023-04-04 | — | — | CN | disclosed |