SCHEMBL30263200

SCHEMBL30263200

NC(=O)c1ccc(C(=O)N2CCOCC2)cc1-c1nc(-c2ccccc2Cl)cs1

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 7/20 0.58
EIF4E P06730 1/20 0.52
CYP1A1 P04798 1/20 0.48
CYP1B1 Q16678 1/20 0.48
KDM4E B2RXH2 1/20 0.47
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
HPGD P15428 3/20 0.47
PKM P14618 1/20 0.46
PDE4B Q07343 1/20 0.46
CCNA2 P20248 1/20 0.44
CDK2 P24941 1/20 0.44
CCNA1 P78396 1/20 0.44
CDK5 Q00535 1/20 0.44
CDK5R1 Q15078 1/20 0.44
JAK2 O60674 1/20 0.43
APC P25054 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30263324 0.88 KDM4E (0.47) HTR2CEIF4ECYP1A1CYP1B1KDM4E
SCHEMBL30263215 0.85 CYP1B1 (0.61) HTR2CEIF4ECYP1A1CYP1B1KDM4E
SCHEMBL30263254 0.79 KDM4E (0.44) HTR2CEIF4ECYP1A1CYP1B1KDM4E
SCHEMBL30263320 0.78 KDM4E (0.53) EIF4ECYP1A1CYP1B1KDM4ENPC1
SCHEMBL30292485 0.78 CYP1A1 (0.53) HTR2CCYP1A1CYP1B1KDM4ENPC1
SCHEMBL30263245 0.76 CYP1A1 (0.51) HTR2CCYP1A1CYP1B1KDM4ENPC1
SCHEMBL24107685 0.76 KMT2A (0.58) HTR2CCYP1A1CYP1B1KDM4ENPC1
SCHEMBL30292583 0.76 KMT2A (0.58) HTR2CCYP1A1CYP1B1KDM4ENPC1
SCHEMBL30263195 0.75 CYP1A1 (0.47) EIF4ECYP1A1CYP1B1KDM4ENPC1
SCHEMBL30263295 0.75 CYP1A1 (0.47) EIF4ECYP1A1CYP1B1KDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4161921-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF Anima Biotech Inc. (US) 2023-04-12 EP disclosed
CN-115916776-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2023-04-04 CN disclosed