SCHEMBL30263245

SCHEMBL30263245

Cc1c(C(N)=O)ccc(N2CCOCC2)c1-c1nc(-c2ccccc2Cl)cs1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 2/20 0.51
CYP1B1 Q16678 2/20 0.51
HTR2C P28335 5/20 0.46
CCNA2 P20248 1/20 0.43
CDK2 P24941 1/20 0.43
CCNA1 P78396 1/20 0.43
CDK5 Q00535 1/20 0.43
CDK5R1 Q15078 1/20 0.43
KDM4E B2RXH2 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
LMNA P02545 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
NSD2 O96028 1/20 0.41
CNR2 P34972 1/20 0.41
MAPK9 P45984 1/20 0.40
MAPK10 P53779 1/20 0.40
KMT2A Q03164 2/20 0.40
AR P10275 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30263251 0.89 CYP1A1 (0.49) CYP1A1CYP1B1HTR2CCCNA2CDK2
SCHEMBL30263302 0.87 CYP1A1 (0.49) CYP1A1CYP1B1HTR2CCCNA2CDK2
SCHEMBL30292485 0.84 CYP1A1 (0.53) CYP1A1CYP1B1HTR2CCCNA2CDK2
SCHEMBL30263215 0.81 CYP1B1 (0.61) CYP1A1CYP1B1HTR2CCCNA2CDK2
SCHEMBL30263192 0.79 CYP1A1 (0.52) CYP1A1CYP1B1HTR2CCCNA2CDK2
SCHEMBL30263345 0.77 CYP1A1 (0.52) CYP1A1CYP1B1HTR2CCCNA2CDK2
SCHEMBL30263185 0.77 CYP1A1 (0.53) CYP1A1CYP1B1HTR2CCCNA2CDK2
SCHEMBL30263200 0.76 HTR2C (0.58) CYP1A1CYP1B1HTR2CCCNA2CDK2
SCHEMBL30263260 0.74 CYP1B1 (0.57) CYP1A1CYP1B1HTR2CCCNA2CDK2
SCHEMBL30263223 0.74 KDM4E (0.51) CYP1A1CYP1B1KDM4ENPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4161921-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF Anima Biotech Inc. (US) 2023-04-12 EP disclosed
CN-115916776-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2023-04-04 CN disclosed