Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | AOC3 | Q16853 | 10/20 | 0.48 |
| ▸ | CCNC | P24863 | 1/20 | 0.46 |
| ▸ | CDK8 | P49336 | 1/20 | 0.46 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23961033 | 1.00 | HRH3 (0.57) | HRH3MAPTKMT2ACASP6GFER | |
| SCHEMBL25246829 | 0.89 | HRH3 (0.57) | HRH3MAPTKMT2AMEN1MAPK1 | |
| SCHEMBL64453 | 0.86 | HRH3 (0.54) | HRH3MAPTKMT2AMAPK1ALDH1A1 | |
| SCHEMBL1912372 | 0.84 | GFER (0.54) | MAPTKMT2ACASP6GFERMEN1 | |
| SCHEMBL14875984 | 0.84 | HRH3 (0.57) | HRH3MAPTKMT2AGFERMEN1 | |
| SCHEMBL31073082 | 0.83 | TRPC6 (0.54) | HRH3MAPTKMT2AMAPK1 | |
| SCHEMBL14802410 | 0.83 | SMN1; SMN2 (0.60) | HRH3MAPTKMT2AMEN1ALK | |
| SCHEMBL29913781 | 0.83 | SMN1; SMN2 (0.60) | HRH3MAPTKMT2AMEN1ALK | |
| SCHEMBL21200374 | 0.82 | CDK4 (0.48) | ALK | |
| SCHEMBL29867057 | 0.82 | CDK4 (0.48) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161921-A1 | COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF | Anima Biotech Inc. (US) | 2023-04-12 | — | — | EP | disclosed |