Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21294575 | 1.00 | ADRA2A (0.39) | ADRA2AADRA2BADRA2CADRA1AIDO1 | |
| SCHEMBL20725128 | 0.82 | ADRA2A (0.43) | ADRA2AADRA2BADRA2CADRA1AIDO1 | |
| SCHEMBL28011816 | 0.74 | IDO1 (0.44) | ADRA2AADRA2BADRA2CADRA1AIDO1 | |
| SCHEMBL145977 | 0.74 | IDO1 (0.57) | ADRA2AADRA1AIDO1 | |
| SCHEMBL29357487 | 0.74 | IDO1 (0.57) | ADRA2AADRA1AIDO1 | |
| Hydrochloric Acid SCHEMBL6542205 | 0.73 | IDO1 (0.45) | ADRA2AADRA2BADRA2CADRA1AIDO1 | |
| SCHEMBL7317272 | 0.71 | ESR1 (0.47) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL10682685 | 0.71 | ESR1 (0.51) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL9391610 | 0.71 | ESR1 (0.47) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL6784204 | 0.70 | IDO1 (0.53) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161921-A1 | COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF | Anima Biotech Inc. (US) | 2023-04-12 | — | — | EP | disclosed |