SCHEMBL30263276

SCHEMBL30263276

COC(=O)c1ccc(OC2CCN(C(=O)OC(C)(C)C)CC2)cn1

nearest known ligand 0.58

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 8/20 0.58
ALDH1A1 P00352 1/20 0.50
EPHX2 P34913 1/20 0.47
NPBWR1 P48145 1/20 0.47
MCHR1 Q99705 1/20 0.47
HRH3 Q9Y5N1 2/20 0.47
CHEK2 O96017 1/20 0.46
STS P08842 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21607020 1.00 GPR119 (0.58) GPR119ALDH1A1EPHX2NPBWR1MCHR1
SCHEMBL31552861 0.94 GPR119 (0.54) GPR119ALDH1A1
SCHEMBL30234643 0.94 GPR119 (0.54) GPR119ALDH1A1
SCHEMBL25282448 0.94 GPR119 (0.54) GPR119ALDH1A1
SCHEMBL29212746 0.94 GPR119 (0.54) GPR119ALDH1A1
SCHEMBL25191966 0.94 GPR119 (0.54) GPR119ALDH1A1
SCHEMBL1698685 0.89 GPR119 (0.57) GPR119ALDH1A1NPBWR1MCHR1CHEK2
SCHEMBL31044638 0.89 GPR119 (0.55) GPR119ALDH1A1NPBWR1MCHR1CHEK2
SCHEMBL25093966 0.89 GPR119 (0.50) GPR119ALDH1A1EPHX2HRH3
SCHEMBL30019202 0.89 GPR119 (0.50) GPR119ALDH1A1EPHX2HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4161921-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF Anima Biotech Inc. (US) 2023-04-12 EP disclosed