Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 2/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 5/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.39 |
| ▸ | EIF4E | P06730 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.38 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.38 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 3/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30292523 | 0.85 | CYP1B1 (0.42) | ARCYP1A1CYP1B1CYP1A2EIF4E | |
| SCHEMBL30263322 | 0.85 | PKMYT1 (0.40) | ATRARCYP1A1CYP1B1CYP1A2 | |
| SCHEMBL30263185 | 0.84 | CYP1A1 (0.53) | ARCYP1A1CYP1B1CYP1A2PIK3CA | |
| SCHEMBL30292589 | 0.82 | AR (0.39) | ATRPIM1PIM3ARCYP1A1 | |
| SCHEMBL30263188 | 0.78 | AOC3 (0.42) | ARCYP1A1CYP1B1CYP1A2EIF4E | |
| SCHEMBL24107575 | 0.74 | L3MBTL1 (0.46) | CNR2 | |
| SCHEMBL30292522 | 0.74 | L3MBTL1 (0.46) | CNR2 | |
| SCHEMBL30263260 | 0.70 | CYP1B1 (0.57) | ARCYP1A1CYP1B1CYP1A2PIK3CA | |
| SCHEMBL24107572 | 0.70 | SMN1; SMN2 (0.46) | — | |
| SCHEMBL24107565 | 0.70 | MPL (0.55) | CYP1A2IKBKETBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161921-A1 | COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF | Anima Biotech Inc. (US) | 2023-04-12 | — | — | EP | disclosed |
| CN-115916776-A | Collagen 1 translation inhibitors and methods of use thereof | 艾尼莫生物科技公司 | 2023-04-04 | — | — | CN | disclosed |