Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 3/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | JAK1 | P23458 | 1/20 | 0.47 |
| ▸ | JAK3 | P52333 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | PARP1 | P09874 | 2/20 | 0.46 |
| ▸ | TNKS | O95271 | 1/20 | 0.46 |
| ▸ | PARP6 | Q2NL67 | 1/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.46 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL30292482 | 0.95 | SYK (0.45) | SYKJAK2JAK1JAK3HRH3 | |
| SCHEMBL30292554 | 0.87 | MAPT (0.49) | POLBMAPTMEN1KMT2ARAB9A | |
| SCHEMBL24107591 | 0.87 | MAPT (0.49) | POLBMAPTMEN1KMT2ARAB9A | |
| SCHEMBL30263290 | 0.84 | HRH3 (0.52) | HRH3POLBMAPTMEN1KMT2A | |
| SCHEMBL24107471 | 0.84 | HRH3 (0.52) | HRH3POLBMAPTMEN1KMT2A | |
| SCHEMBL28145051 | 0.81 | HRH3 (0.54) | HRH3PARP1TNKSPARP6PARP2 | |
| SCHEMBL21245746 | 0.80 | GCKR (0.52) | POLBMAPTMEN1KMT2ARAB9A | |
| SCHEMBL15651285 | 0.79 | HRH3 (0.53) | SYKHRH3POLBPARP1TNKS | |
| SCHEMBL12697202 | 0.78 | CHEK1 (0.51) | POLBMAPTMEN1KMT2ARAB9A | |
| SCHEMBL4985685 | 0.78 | MAPT (0.59) | POLBMAPTMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161921-A1 | COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF | Anima Biotech Inc. (US) | 2023-04-12 | — | — | EP | disclosed |