Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 9/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24107471 | 1.00 | HRH3 (0.52) | HRH3POLBGLATSHRMAPK1 | |
| SCHEMBL30292554 | 0.85 | MAPT (0.49) | POLBMAPTRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL24107591 | 0.85 | MAPT (0.49) | POLBMAPTRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL30263293 | 0.84 | SYK (0.47) | HRH3POLBMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL64453 | 0.83 | HRH3 (0.54) | HRH3MAPK1MAPTRAB9AALDH1A1 | |
| SCHEMBL14875984 | 0.82 | HRH3 (0.57) | HRH3MAPK1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL25246829 | 0.81 | HRH3 (0.57) | HRH3TSHRMAPK1MAPTRAB9A | |
| SCHEMBL23961033 | 0.81 | HRH3 (0.57) | HRH3MAPK1MAPTALDH1A1MEN1 | |
| SCHEMBL31073082 | 0.81 | TRPC6 (0.54) | HRH3MAPK1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL30263227 | 0.81 | HRH3 (0.57) | HRH3MAPK1MAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161921-A1 | COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF | Anima Biotech Inc. (US) | 2023-04-12 | — | — | EP | disclosed |