SCHEMBL30263333

SCHEMBL30263333

COC(=O)c1ccc(C2CCSCC2)cn1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.50
KDM4E B2RXH2 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
GLA P06280 1/20 0.49
HTT P42858 1/20 0.49
KMT2A Q03164 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
HIF1A Q16665 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
HRH3 Q9Y5N1 2/20 0.38
DYRK1A Q13627 1/20 0.37
PARP1 P09874 1/20 0.36
LCK P06239 1/20 0.36
TRPC6 Q9Y210 1/20 0.36
PDE7A Q13946 1/20 0.36
JAK2 O60674 1/20 0.36
JAK1 P23458 1/20 0.36
GPR119 Q8TDV5 1/20 0.35
GABRA1 P14867 1/20 0.35
GABRG2 P18507 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24107474 1.00 MAPK1 (0.50) MAPK1KDM4EL3MBTL1GLAHTT
SCHEMBL25953857 0.90 MAPK1 (0.57) MAPK1KDM4EL3MBTL1GLAHTT
SCHEMBL14152280 0.90 MAPK1 (0.57) MAPK1KDM4EL3MBTL1GLAHTT
SCHEMBL31589442 0.87 KDM4E (0.65) MAPK1KDM4EL3MBTL1GLAHTT
SCHEMBL23530224 0.87 KDM4E (0.60) MAPK1KDM4EL3MBTL1GLAHTT
SCHEMBL27995000 0.84 MAPK1 (0.51) MAPK1KDM4EL3MBTL1GLAHTT
SCHEMBL24107756 0.83 MAPK1 (0.50) MAPK1KDM4EL3MBTL1GLAHTT
SCHEMBL24244939 0.83 MAPK1 (0.50) MAPK1KDM4EL3MBTL1GLAHTT
SCHEMBL30263210 0.83 MAPK1 (0.50) MAPK1KDM4EL3MBTL1GLAHTT
SCHEMBL27994759 0.83 MAPK1 (0.50) MAPK1KDM4EL3MBTL1GLAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4161921-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF Anima Biotech Inc. (US) 2023-04-12 EP disclosed