SCHEMBL30263672

SCHEMBL30263672

NCCCC[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)CO)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ ERAP2 Q6P179 1/20 0.56
▸ LNPEP Q9UIQ6 1/20 0.56
▸ NPY4R P50391 4/20 0.55
▸ NPY1R P25929 3/20 0.55
▸ NPY2R P49146 3/20 0.55
▸ ENPEP Q07075 2/20 0.52
▸ CHRNA1 P02708 1/20 0.48
▸ CHRNG P07510 1/20 0.48
▸ CHRNB1 P11230 1/20 0.48
▸ CHRND Q07001 1/20 0.48
▸ NTSR2 O95665 2/20 0.48
▸ NTSR1 P30989 2/20 0.48
▸ NPY5R Q15761 2/20 0.48
▸ GNPAT O15228 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31135152 1.00 ERAP2 (0.56) ERAP2LNPEPNPY4RNPY1RNPY2R
SCHEMBL31031465 0.98 ERAP2 (0.54) ERAP2LNPEPNPY4RNPY1RNPY2R
SCHEMBL30973975 0.98 ERAP2 (0.54) ERAP2LNPEPNPY4RNPY1RNPY2R
SCHEMBL29680070 0.94 NPY1R (0.56) ERAP2LNPEPNPY4RNPY1RNPY2R
SCHEMBL30974367 0.93 NPY4R (0.58) ERAP2LNPEPNPY4RNPY1RNPY2R
Lysyl-Tyrosyl-Lysine Acetate SCHEMBL6275116 0.93 NPY4R (0.62) ERAP2LNPEPNPY4RNPY1RNPY2R
SCHEMBL30523264 0.93 LNPEP (0.63) ERAP2LNPEPNPY4RNPY1RNPY2R
Lysyl-Tyrosyl-Lysine Acetate SCHEMBL6275111 0.93 NPY4R (0.62) ERAP2LNPEPNPY4RNPY1RNPY2R
SCHEMBL27942027 0.93 NPY4R (0.62) ERAP2LNPEPNPY4RNPY1RNPY2R
SCHEMBL30931517 0.92 LNPEP (0.62) ERAP2LNPEPNPY4RNPY1RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250324933-A1 Crown Rot Resistance COMMW SCIENT IND RES ORG (AU) 2025-10-23 — — US disclosed
US-20250188500-A1 METHODS AND SYSTEMS FOR DEPOLYMERIZING POLYAMIDES Alliance for Energy Innovation, LLC 2025-06-12 — — US disclosed
CN-116200352-B 7 Alpha-hydroxysteroid dehydrogenase mutant and application thereof in 7-oxo-lithocholic acid synthesis 江南大学 2025-06-03 — — CN disclosed
WO-2025064408-A1 COMPOSITIONS AND METHODS FOR TREATING CARDIOVASCULAR DISEASE THE BROAD INSTITUTE, INC. (US) 2025-03-27 — — WO disclosed
WO-2025044960-A1 KETOREDUCTASE MUTANT AND USE THEREOF 华南理工大学 2025-03-06 — — WO disclosed
US-12138285-B2 Cholesterol reducing compositions and methods of use thereof NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-11-12 — — US disclosed
CN-118524779-A Crown rot resistance 联邦科学技术研究组织 2024-08-20 — — CN disclosed
CN-113151205-B Alcohol dehydrogenase mutant and application thereof in synthesis of cyclic terpene ketone 苏州百福安酶技术有限公司 2024-07-16 — — CN disclosed
EP-4391796-A1 CROWN ROT RESISTANCE Commonwealth Scientific and Industrial Research Organisation (AU) 2024-07-03 — — EP disclosed
WO-2024132726-A1 SERUM PEPTIDE PATTERNS FOR DIAGNOSTICS OF ACUTE ISCHEMIC STROKE IN HUMANS AND DIFFERENTIAL DIAGNOSIS OF ACUTE ISCHEMIC STROKE FROM INTRACRANIAL HEMORRHAGIC STROKE UNIWERSYTET GDANSKI (PL) 2024-06-27 — — WO disclosed
CN-117126823-B Ketone reductase mutant and application thereof 华南理工大学 2024-03-29 — — CN disclosed
US-20240024381-A1 CHOLESTEROL REDUCING COMPOSITIONS AND METHODS OF USE THEREOF NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-01-25 — — US disclosed
CN-117126823-A Ketone reductase mutant and application thereof 华南理工大学 2023-11-28 — — CN disclosed
CN-116200352-A 7 alpha-hydroxysteroid dehydrogenase mutant and application thereof in 7-oxo-lithocholic acid synthesis 江南大学 2023-06-02 — — CN disclosed
US-11633436-B2 Cholesterol reducing compositions and methods of use thereof THE BROAD INSTITUTE, INC. (US) 2023-04-25 — — US disclosed
WO-2023023719-A1 CROWN ROT RESISTANCE COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2023-03-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240024381-A1 CHOLESTEROL REDUCING COMPOSITIONS AND METHODS OF USE THEREOF CETP, DHCR7, HMGCR ERAP2 2066/4885LNPEP 1161/4885NPY4R 4714/4885
US-11633436-B2 Cholesterol reducing compositions and methods of use thereof CETP, DHCR7, HMGCR ERAP2 2066/4885LNPEP 1161/4885NPY4R 4714/4885
US-12138285-B2 Cholesterol reducing compositions and methods of use thereof CETP, DHCR7, HMGCR ERAP2 2066/4885LNPEP 1161/4885NPY4R 4714/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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