Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 9/20 | 0.46 |
| ▸ | SRC | P12931 | 8/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 8/20 | 0.46 |
| ▸ | MTOR | P42345 | 7/20 | 0.46 |
| ▸ | PRKDC | P78527 | 7/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 6/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.46 |
| ▸ | KDR | P35968 | 6/20 | 0.46 |
| ▸ | ABL1 | P00519 | 5/20 | 0.46 |
| ▸ | HCK | P08631 | 5/20 | 0.46 |
| ▸ | EPHB4 | P54760 | 5/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.37 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.36 |
| ▸ | PIK3C2B | O00750 | 2/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | TEK | Q02763 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30264739 | 0.83 | EGFR (0.42) | EGFRSRCPIK3CDMTORPRKDC | |
| SCHEMBL20162797 | 0.81 | CYP1A2 (0.40) | EGFRSRCKDRABL1HCK | |
| SCHEMBL30264709 | 0.80 | SRC (0.48) | EGFRSRCPIK3CDMTORPRKDC | |
| SCHEMBL15487063 | 0.80 | SRC (0.48) | EGFRSRCPIK3CDMTORPRKDC | |
| SCHEMBL30264648 | 0.79 | EGFR (0.38) | EGFRSRCPIK3CDMTORPRKDC | |
| SCHEMBL26105112 | 0.78 | NPC1 (0.36) | EGFRKDRLCKTEK | |
| SCHEMBL15220890 | 0.77 | EGFR (0.46) | EGFRSRCPIK3CDMTORPRKDC | |
| SCHEMBL30264595 | 0.77 | EGFR (0.40) | EGFRSRCPIK3CDMTORPRKDC | |
| SCHEMBL15221069 | 0.76 | EGFR (0.47) | EGFRSRCPIK3CDMTORPRKDC | |
| SCHEMBL19562034 | 0.76 | EGFR (0.47) | EGFRSRCPIK3CDMTORPRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4392423-A1 | QUINAZOLINE COMPOUNDS FOR TREATMENT OF DISEASE | Arthrosi Therapeutics, Inc. (US) | 2024-07-03 | — | — | EP | disclosed |
| WO-2023028054-A1 | QUINAZOLINE COMPOUNDS FOR TREATMENT OF DISEASE | ARTHROSI THERAPEUTICS, INC. (US) | 2023-03-02 | — | — | WO | disclosed |