SCHEMBL30264596

SCHEMBL30264596

C[C@@H](NC(=O)[C@H](CS)NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CS)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ ACE P12821 2/20 0.53
▸ KISS1R Q969F8 2/20 0.51
▸ ECE1 P42892 7/20 0.50
▸ IL23R Q5VWK5 1/20 0.50
▸ NPBWR1 P48145 1/20 0.49
▸ NPY1R P25929 2/20 0.48
▸ NPY2R P49146 2/20 0.48
▸ NPY4R P50391 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30264981 1.00 ACE (0.53) ACEKISS1RECE1IL23RNPBWR1
SCHEMBL29511013 0.98 ACE (0.55) ACEKISS1RECE1
SCHEMBL29511038 0.98 ACE (0.55) ACEKISS1RECE1
SCHEMBL30264819 0.97 KISS1R (0.55) ACEKISS1RIL23RNPBWR1NPY1R
SCHEMBL30264867 0.97 KISS1R (0.55) ACEKISS1RIL23RNPBWR1NPY1R
SCHEMBL30264784 0.97 KISS1R (0.55) ACEKISS1RIL23RNPBWR1NPY1R
SCHEMBL30264955 0.97 KISS1R (0.55) ACEKISS1RIL23RNPBWR1NPY1R
SCHEMBL30264824 0.97 KISS1R (0.55) ACEKISS1RIL23RNPBWR1NPY1R
SCHEMBL30264852 0.97 KISS1R (0.55) ACEKISS1RIL23RNPBWR1NPY1R
SCHEMBL30265048 0.95 KISS1R (0.53) KISS1RIL23RNPBWR1NPY1RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240391954-A1 MC4R AGONIST PEPTIDES THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2024-11-28 — — US disclosed
EP-4392072-A1 MC4R AGONIST PEPTIDES The Regents Of The University Of Michigan (US) 2024-07-03 — — EP disclosed
WO-2023028538-A1 MC4R AGONIST PEPTIDES THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2023-03-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240391954-A1 MC4R AGONIST PEPTIDES MC4R, MC3R, MC5R ACE 3813/4885KISS1R 72/4885ECE1 2505/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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