Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.54 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.54 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.54 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.54 |
| ▸ | PDE4A | P27815 | 2/20 | 0.54 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.54 |
| ▸ | EGFR | P00533 | 12/20 | 0.50 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.50 |
| ▸ | BRAF | P15056 | 1/20 | 0.49 |
| ▸ | NSD2 | O96028 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29465791 | 0.88 | PIK3CD (0.54) | PIK3CDPIK3CAPIK3CBPIK3CGPDE4B | |
| SCHEMBL2453138 | 0.88 | PIK3CD (0.54) | PIK3CDPIK3CAPIK3CBPIK3CGPDE4B | |
| SCHEMBL29465790 | 0.88 | PIK3CD (0.54) | PIK3CDPIK3CAPIK3CBPIK3CGPDE4B | |
| SCHEMBL665187 | 0.88 | PIK3CD (0.54) | PIK3CDPIK3CAPIK3CBPIK3CGPDE4B | |
| SCHEMBL5828984 | 0.87 | EPHA2 (0.50) | PIK3CDPIK3CAPIK3CBPIK3CGERBB2 | |
| SCHEMBL30264767 | 0.87 | PIK3CD (0.53) | PIK3CDPIK3CAPIK3CBPIK3CGPDE4B | |
| SCHEMBL28983513 | 0.84 | PIK3CD (0.49) | PIK3CDPIK3CAPIK3CBPIK3CGPDE4B | |
| SCHEMBL29686088 | 0.84 | PIK3CD (0.49) | PIK3CDPIK3CAPIK3CBPIK3CGPDE4B | |
| SCHEMBL28983490 | 0.83 | PIK3CD (0.48) | PIK3CDPIK3CAPIK3CBPIK3CGPDE4B | |
| SCHEMBL30264797 | 0.83 | PDE10A (0.62) | PIK3CDPIK3CAPIK3CBPIK3CGPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4392423-A1 | QUINAZOLINE COMPOUNDS FOR TREATMENT OF DISEASE | Arthrosi Therapeutics, Inc. (US) | 2024-07-03 | — | — | EP | disclosed |
| WO-2023028054-A1 | QUINAZOLINE COMPOUNDS FOR TREATMENT OF DISEASE | ARTHROSI THERAPEUTICS, INC. (US) | 2023-03-02 | — | — | WO | disclosed |