SCHEMBL30264776

SCHEMBL30264776

CCCC[C@H](NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CS)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ NPY1R P25929 3/20 0.55
▸ NPY2R P49146 3/20 0.55
▸ NPY4R P50391 3/20 0.55
▸ IL23R Q5VWK5 3/20 0.53
▸ KISS1R Q969F8 5/20 0.51
▸ ERAP2 Q6P179 2/20 0.51
▸ ERAP1 Q9NZ08 2/20 0.51
▸ LNPEP Q9UIQ6 2/20 0.51
▸ MC4R P32245 2/20 0.51
▸ CCKAR P32238 1/20 0.51
▸ CCKBR P32239 1/20 0.51
▸ OPRD1 P41143 1/20 0.51
▸ GHSR Q92847 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30264689 1.00 NPY1R (0.55) NPY1RNPY2RNPY4RIL23RKISS1R
SCHEMBL30264615 0.98 NPY1R (0.53) NPY1RNPY2RNPY4RIL23RKISS1R
SCHEMBL30264740 0.98 NPY1R (0.53) NPY1RNPY2RNPY4RIL23RKISS1R
SCHEMBL30265032 0.98 NPY1R (0.53) NPY1RNPY2RNPY4RIL23RKISS1R
SCHEMBL30264762 0.97 IL23R (0.55) NPY1RNPY2RNPY4RIL23RERAP2
SCHEMBL30029375 0.96 ERAP2 (0.54) NPY1RNPY2RNPY4RIL23RERAP2
SCHEMBL30264867 0.94 KISS1R (0.55) NPY1RNPY2RNPY4RIL23RKISS1R
SCHEMBL30264955 0.94 KISS1R (0.55) NPY1RNPY2RNPY4RIL23RKISS1R
SCHEMBL30264819 0.94 KISS1R (0.55) NPY1RNPY2RNPY4RIL23RKISS1R
SCHEMBL30264795 0.94 NPY1R (0.52) NPY1RNPY2RNPY4RIL23RKISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240391954-A1 MC4R AGONIST PEPTIDES THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2024-11-28 — — US disclosed
EP-4392072-A1 MC4R AGONIST PEPTIDES The Regents Of The University Of Michigan (US) 2024-07-03 — — EP disclosed
WO-2023028538-A1 MC4R AGONIST PEPTIDES THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2023-03-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240391954-A1 MC4R AGONIST PEPTIDES MC4R, MC3R, MC5R NPY1R 9/4885NPY2R 17/4885NPY4R 6/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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