Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MPO | P05164 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 2/20 | 0.52 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.51 |
| ▸ | MC4R | P32245 | 2/20 | 0.50 |
| ▸ | MC5R | P33032 | 1/20 | 0.50 |
| ▸ | MC3R | P41968 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29603261 | 0.96 | KDM4E (0.59) | GHSRKDM4EMEN1LMNAMPO | |
| SCHEMBL31468788 | 0.94 | GHSR (0.61) | GHSRKDM4EMEN1LMNAMPO | |
| SCHEMBL1387764 | 0.94 | KDM4E (0.61) | GHSRKDM4EMEN1LMNAMPO | |
| SCHEMBL29382469 | 0.94 | KDM4E (0.61) | GHSRKDM4EMEN1LMNAMPO | |
| SCHEMBL29404993 | 0.94 | KDM4E (0.61) | GHSRKDM4EMEN1LMNAMPO | |
| SCHEMBL3048070 | 0.94 | KDM4E (0.61) | GHSRKDM4EMEN1LMNAMPO | |
| SCHEMBL29721506 | 0.94 | KDM4E (0.61) | GHSRKDM4EMEN1LMNAMPO | |
| SCHEMBL1711405 | 0.94 | KDM4E (0.61) | GHSRKDM4EMEN1LMNAMPO | |
| SCHEMBL14906252 | 0.94 | KDM4E (0.61) | GHSRKDM4EMEN1LMNAMPO | |
| SCHEMBL27542236 | 0.94 | KDM4E (0.61) | GHSRKDM4EMEN1LMNAMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4392440-A2 | COMBINATION OF RELAXIN AND VASOPRESSIN ANALOGUES FOR TREATMENT OF RENAL DISORDERS OR CONDITIONS | River 2 Renal Corp. (US) | 2024-07-03 | — | — | EP | disclosed |
| WO-2023028008-A2 | COMBINATION OF RELAXIN AND VASOPRESSIN ANALOGUES FOR TREATMENT OF RENAL DISORDERS OR CONDITIONS | RIVER 2 RENAL CORP. (US) | 2023-03-02 | — | — | WO | disclosed |