Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | TDO2 | P48775 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MPO | P05164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19972562 | 1.00 | IDO1 (0.34) | IDO1TDO2KDM4EHTTLMNA | |
| SCHEMBL19972520 | 0.87 | CYP3A4 (0.40) | CYP3A4 | |
| SCHEMBL31001184 | 0.87 | CYP3A4 (0.40) | CYP3A4 | |
| SCHEMBL31001181 | 0.83 | IDO1 (0.34) | IDO1TDO2KDM4EHTTLMNA | |
| SCHEMBL19972575 | 0.83 | IDO1 (0.34) | IDO1TDO2KDM4EHTTLMNA | |
| SCHEMBL27197445 | 0.82 | IDO1 (0.34) | IDO1TDO2KDM4EHTTLMNA | |
| SCHEMBL30266044 | 0.82 | IDO1 (0.34) | IDO1TDO2KDM4EHTTLMNA | |
| SCHEMBL19972522 | 0.82 | IDO1 (0.34) | IDO1TDO2KDM4EHTTLMNA | |
| SCHEMBL26006977 | 0.80 | IDO1 (0.33) | IDO1TDO2KDM4EHTTLMNA | |
| SCHEMBL19972638 | 0.79 | CDK9 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512850-B1 | INHIBITORS OF THE MENIN-MLL INTERACTION | VITAE PHARMACEUTICALS LLC (US) | 2023-04-12 | — | — | EP | claimed |