Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 12/20 | 0.45 |
| ▸ | SMPD3 | Q9NY59 | 7/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30267223 | 0.90 | NTRK1 (0.47) | IRAK4SMPD3 | |
| SCHEMBL21997557 | 0.85 | IRAK4 (0.47) | IRAK4SMPD3 | |
| SCHEMBL30267093 | 0.84 | TGFBR1 (0.44) | IRAK4 | |
| SCHEMBL25339230 | 0.83 | IRAK4 (0.46) | IRAK4SMPD3 | |
| SCHEMBL25338786 | 0.83 | IRAK4 (0.45) | IRAK4 | |
| SCHEMBL25339224 | 0.79 | IRAK4 (0.51) | IRAK4SMPD3 | |
| SCHEMBL25339215 | 0.79 | SMPD3 (0.58) | IRAK4SMPD3 | |
| SCHEMBL18208677 | 0.79 | SMPD3 (0.62) | IRAK4SMPD3 | |
| SCHEMBL21996850 | 0.78 | SMPD3 (0.63) | IRAK4SMPD3 | |
| SCHEMBL21997356 | 0.76 | SMPD3 (0.52) | IRAK4SMPD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119894895-A | IRAK4 degradation agent and application thereof | 领泰生物医药(绍兴)有限公司 | 2025-04-25 | — | — | CN | disclosed |
| WO-2023025159-A1 | IRAK4 DEGRADATION AGENT, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海领泰生物医药科技有限公司 | 2023-03-02 | — | — | WO | disclosed |
| CN-115710274-A | IRAK4 degradation agent, preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2023-02-24 | — | — | CN | disclosed |