⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1047067 | 1.00 | — | — | |
| SCHEMBL14748132 | 0.78 | — | — | |
| SCHEMBL7675997 | 0.78 | — | — | |
| SCHEMBL12045939 | 0.74 | — | — | |
| SCHEMBL10711568 | 0.74 | ADH1B (0.31) | — | |
| SCHEMBL16384617 | 0.74 | — | — | |
| SCHEMBL7678682 | 0.74 | — | — | |
| SCHEMBL7674472 | 0.74 | — | — | |
| SCHEMBL11009729 | 0.73 | — | — | |
| SCHEMBL21185158 | 0.72 | EPHX1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487806-B1 | 4-ANILINO QUINAZOLINE DERIVATIVES AS ANTIPROLIFERATIVE AGENTS | ASTRAZENECA AB (SE) | 2010-07-07 | — | — | EP | claimed |
| CN-100439344-C | 4-Anilinoquinazoline derivatives as antiproliferative agents | ASTRAZENECA AB (SE) | 2008-12-03 | — | — | CN | claimed |
| US-6380197-B1 | FOR TREATING AND PREVENTING A PLETHORA OF DISEASES INCLUDING DIABETES | AVENTIS PHARMA S. A. (FR) | 2002-04-30 | — | — | US | claimed |
| EP-1001943-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | Aventis Pharma S.A. (FR) | 2000-05-24 | — | — | EP | claimed |
| CN-1227466-A | Substituted cyclopentane compounds useful as neuraminidase inhibitors | BIOCRYST PHARM INC (US) | 1999-09-01 | — | — | CN | claimed |
| WO-1999003843-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | RHONE-POULENC RORER S.A. (FR) | 1999-01-28 | — | — | WO | claimed |
| CN-107266421-B | Substituted benzimidazole derivatives | 正大天晴药业集团股份有限公司 | 2020-12-04 | — | — | CN | disclosed |
| CN-105316049-B | The solvable quaternary ammonium carboxylate of alkyl and the fuel composition containing them | 雅富顿化学公司 | 2018-06-15 | — | — | CN | disclosed |
| US-9416054-B2 | Alkyl-modified vinyl acetal polymer, and composition | KURARAY CO., LTD. (JP) | 2016-08-16 | — | — | US | disclosed |
| EP-1957073-B1 | MEDICINAL DRUG | OTSUKA PHARMA CO LTD (JP) | 2014-04-23 | — | — | EP | disclosed |
| US-20140018488-A1 | ALKYL-MODIFIED VINYL ACETAL POLYMER, AND COMPOSITION | KURARAY CO., LTD. (JP) | 2014-01-16 | — | — | US | disclosed |
| US-8551999-B2 | Heterocyclic compound and pharmaceutical composition thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-10-08 | — | — | US | disclosed |
| EP-2612858-A1 | STAT3/5 activation inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-07-10 | — | — | EP | disclosed |
| EP-0450097-B1 | BENZOHETEROCYCLIC COMPOUNDS | OTSUKA PHARMA CO LTD (JP) | 1996-04-24 | — | — | EP | disclosed |
| CN-1108250-A | Substituted carbamoyltriazoles | BAYER AG (DE) | 1995-09-13 | — | — | CN | disclosed |
| EP-0602209-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |
| WO-1994001113-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1994-01-20 | — | — | WO | disclosed |
| EP-0450097-A1 | BENZOHETEROCYCLIC COMPOUNDS. | OTSUKA PHARMA CO LTD (JP) | 1991-10-09 | — | — | EP | disclosed |
| WO-1991005549-A1 | BENZOHETEROCYCLIC COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-02 | — | — | WO | disclosed |
| EP-0217372-A2 | Polyoxygenated labdane derivatives, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-04-08 | — | — | EP | disclosed |