Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 12/20 | 0.69 |
| ▸ | VEGFA | P15692 | 11/20 | 0.69 |
| ▸ | CNR2 | P34972 | 3/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL278141 | 0.88 | EGLN1 (0.79) | EGLN1VEGFACNR2CNR1KDM4E | |
| SCHEMBL273303 | 0.82 | EGLN1 (1.00) | EGLN1VEGFACNR2CNR1KDM4E | |
| SCHEMBL19478702 | 0.81 | EGLN1 (0.68) | EGLN1VEGFACNR2CNR1KDM4E | |
| SCHEMBL12598838 | 0.80 | EGLN1 (0.82) | EGLN1VEGFACNR2CNR1KDM4E | |
| SCHEMBL272935 | 0.80 | EGLN1 (1.00) | EGLN1VEGFACNR2CNR1KDM4E | |
| SCHEMBL271477 | 0.80 | VEGFA (0.76) | EGLN1VEGFABCHEACHEBACE1 | |
| SCHEMBL19478697 | 0.79 | EGLN1 (0.78) | EGLN1VEGFAKDM4EBCHEACHE | |
| SCHEMBL16789163 | 0.79 | EGLN1 (0.78) | EGLN1VEGFACNR2CNR1KDM4E | |
| SCHEMBL27636343 | 0.79 | EGLN1 (0.65) | EGLN1VEGFACNR2CNR1KDM4E | |
| SCHEMBL272882 | 0.78 | VEGFA (0.70) | EGLN1VEGFABCHEACHEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4142721-A1 | HYPOXIA-INDUCIBLE FACTOR PROLYL HYDROXYLASE INHIBITORS FOR TREATING AGING-RELATED CONDITIONS | Bioage Labs, Inc. (US) | 2023-03-08 | — | — | EP | disclosed |