Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 17/20 | 0.53 |
| ▸ | THRA | P10827 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.53 |
| ▸ | FTO | Q9C0B1 | 8/20 | 0.49 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.49 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.44 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.43 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.43 |
| ▸ | KDM6B | O15054 | 3/20 | 0.42 |
| ▸ | KDM3A | Q9Y4C1 | 3/20 | 0.42 |
| ▸ | HIF1AN | Q9NWT6 | 2/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL964764 | 1.00 | EGLN1 (0.53) | EGLN1THRATHRBFTOBBOX1 | |
| SCHEMBL964867 | 0.90 | EGLN1 (0.53) | EGLN1THRATHRBFTOBBOX1 | |
| SCHEMBL30274587 | 0.86 | EGLN1 (0.64) | EGLN1THRATHRBFTOBBOX1 | |
| SCHEMBL968184 | 0.86 | EGLN1 (0.64) | EGLN1THRATHRBFTOBBOX1 | |
| SCHEMBL967787 | 0.85 | EGLN1 (0.60) | EGLN1THRATHRBFTOBBOX1 | |
| SCHEMBL30274451 | 0.81 | EGLN1 (0.62) | EGLN1FTOBBOX1EGLN2 | |
| SCHEMBL965014 | 0.81 | EGLN1 (0.62) | EGLN1FTOBBOX1EGLN2 | |
| SCHEMBL965570 | 0.81 | EGLN1 (0.51) | EGLN1THRATHRBFTOBBOX1 | |
| SCHEMBL966064 | 0.81 | EGLN1 (0.52) | EGLN1THRATHRBFTOBBOX1 | |
| SCHEMBL27761902 | 0.81 | EGLN1 (0.47) | EGLN1THRATHRBFTOBBOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4142721-A1 | HYPOXIA-INDUCIBLE FACTOR PROLYL HYDROXYLASE INHIBITORS FOR TREATING AGING-RELATED CONDITIONS | Bioage Labs, Inc. (US) | 2023-03-08 | — | — | EP | disclosed |