SCHEMBL30274451

SCHEMBL30274451

N#Cc1nc(C(=O)NCC(=O)O)c(O)c2sccc12

nearest known ligand 0.62

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 20/20 0.62
BBOX1 O75936 1/20 0.46
FTO Q9C0B1 1/20 0.46
EGLN2 Q96KS0 7/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL965014 1.00 EGLN1 (0.62) EGLN1BBOX1FTOEGLN2
SCHEMBL968962 0.91 EGLN1 (0.59) EGLN1BBOX1FTOEGLN2
SCHEMBL965570 0.88 EGLN1 (0.51) EGLN1BBOX1FTOEGLN2
SCHEMBL30274587 0.83 EGLN1 (0.64) EGLN1BBOX1FTOEGLN2
SCHEMBL968184 0.83 EGLN1 (0.64) EGLN1BBOX1FTOEGLN2
SCHEMBL967787 0.81 EGLN1 (0.60) EGLN1BBOX1FTO
SCHEMBL30274332 0.81 EGLN1 (0.53) EGLN1BBOX1FTOEGLN2
SCHEMBL964764 0.81 EGLN1 (0.53) EGLN1BBOX1FTOEGLN2
SCHEMBL30274519 0.81 EGLN1 (0.49) EGLN1BBOX1FTO
SCHEMBL969743 0.81 EGLN1 (0.49) EGLN1BBOX1FTO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4142721-A1 HYPOXIA-INDUCIBLE FACTOR PROLYL HYDROXYLASE INHIBITORS FOR TREATING AGING-RELATED CONDITIONS Bioage Labs, Inc. (US) 2023-03-08 EP disclosed