Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 7/20 | 0.58 |
| ▸ | CASP6 | P55212 | 5/20 | 0.58 |
| ▸ | CASP8 | Q14790 | 5/20 | 0.58 |
| ▸ | CTSB | P07858 | 2/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24939272 | 1.00 | CASP3 (0.58) | CASP3CASP6CASP8CTSBCTSS | |
| SCHEMBL30277028 | 0.94 | CASP3 (0.60) | CASP3CASP6CASP8 | |
| SCHEMBL25855238 | 0.94 | CASP3 (0.60) | CASP3CASP6CASP8 | |
| SCHEMBL25855233 | 0.92 | CASP3 (0.57) | CASP3CASP6CASP8CTSBCTSL | |
| SCHEMBL24939425 | 0.92 | CASP3 (0.51) | CASP3CASP6CASP8CTSBCTSL | |
| SCHEMBL30276934 | 0.92 | CASP3 (0.51) | CASP3CASP6CASP8CTSBCTSL | |
| SCHEMBL25307799 | 0.91 | CASP3 (0.50) | CASP3CASP6CASP8CTSBCTSL | |
| SCHEMBL30277009 | 0.91 | CASP3 (0.50) | CASP3CASP6CASP8CTSBCTSL | |
| SCHEMBL24939265 | 0.91 | CASP3 (0.50) | CASP3CASP6CASP8CTSBCTSL | |
| SCHEMBL25307796 | 0.91 | CASP3 (0.50) | CASP3CASP6CASP8CTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4352040-A1 | PROTEASE INHIBITORS FOR THE TREATMENT OF CORONAVIRUS INFECTIONS | The Scripps Research Institute (US) | 2024-04-17 | — | — | EP | claimed |
| WO-2022261473-A1 | PROTEASE INHIBITORS FOR THE TREATMENT OF CORONAVIRUS INFECTIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2022-12-15 | — | — | WO | claimed |
| EP-4352040-A1 | PROTEASE INHIBITORS FOR THE TREATMENT OF CORONAVIRUS INFECTIONS | The Scripps Research Institute (US) | 2024-04-17 | — | — | EP | disclosed |
| WO-2022261473-A1 | PROTEASE INHIBITORS FOR THE TREATMENT OF CORONAVIRUS INFECTIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2022-12-15 | — | — | WO | disclosed |