Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 4/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 6/20 | 0.44 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GPX4 | P36969 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30277584 | 0.93 | HPGD (0.43) | PTGESALOX5HPGDRXRANR1H4 | |
| SCHEMBL30277639 | 0.91 | NPSR1 (0.43) | PTGESALOX5HPGDRXRANR1H4 | |
| SCHEMBL30277512 | 0.88 | PTGES (0.58) | PTGESALOX5RXRALTC4SNR1H4 | |
| SCHEMBL30277581 | 0.87 | PTGES (0.66) | PTGESALOX5RXRALTC4SNR1H4 | |
| SCHEMBL30277574 | 0.85 | PTGES (0.58) | PTGESALOX5RXRALTC4SNR1H4 | |
| SCHEMBL30277622 | 0.85 | PTGES (0.56) | PTGESALOX5HPGDRXRALTC4S | |
| SCHEMBL30277675 | 0.85 | PTGES (0.56) | PTGESALOX5RXRALTC4SNR1H4 | |
| SCHEMBL30277472 | 0.85 | PTGES (0.56) | PTGESALOX5RXRALTC4SNR1H4 | |
| SCHEMBL30277679 | 0.83 | PTGES (0.49) | PTGESALOX5RXRALTC4SNR1H4 | |
| SCHEMBL30277736 | 0.80 | HSP90AA1 (0.60) | PTGESALOX5RXRAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240398823-A1 | DUAL INHIBITOR OF HISTONE DEACETYLASE 6 AND HEAT SHOCK PROTEIN 90 | TAIPEI MEDICAL UNIVERSITY (TW) | 2024-12-05 | — | — | US | disclosed |
| EP-4399198-A2 | DUAL INHIBITOR OF HISTONE DEACETYLASE 6 AND HEAT SHOCK PROTEIN 90 | Taipei Medical University (TW) | 2024-07-17 | — | — | EP | disclosed |
| WO-2023035005-A2 | DUAL INHIBITOR OF HISTONE DEACETYLASE 6 AND HEAT SHOCK PROTEIN 90 | TAIPEI MEDICAL UNIVERSITY (TW) | 2023-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240398823-A1 | DUAL INHIBITOR OF HISTONE DEACETYLASE 6 AND HEAT SHOCK PROTEIN 90 | HSP90AB1, HDAC6, HSP90AB2P | PTGES 3411/4885ALOX5 4457/4885HPGD 1329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.