SCHEMBL30277947

CC[C@H](C)[C@H](N)C(=O)N[C@H](C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)O)[C@@H](C)CC)[C@@H](C)O

nearest known ligand 0.65

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	GLP1R	P43220	11/20	0.65

▸	CCKBR	P32239	4/20	0.65

▸	NPY1R	P25929	1/20	0.63

▸	NPY2R	P49146	1/20	0.63

▸	NPY4R	P50391	1/20	0.63

▸	NPY5R	Q15761	1/20	0.63

▸	CALCR	P30988	4/20	0.63

▸	HCRTR1	O43613	1/20	0.59

▸	HCRTR2	O43614	1/20	0.59

▸	NMBR	P28336	1/20	0.56

▸	GRPR	P30550	1/20	0.56

▸	CRHR1	P34998	1/20	0.56

▸	CRHR2	Q13324	1/20	0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30906533	0.98	GLP1R (0.62)	GLP1RCCKBRNPY1RNPY2RNPY4R
SCHEMBL31000923	0.94	GLP1R (0.68)	GLP1RCCKBRNPY1RNPY2RNPY4R
SCHEMBL30906404	0.94	NPY2R (0.65)	GLP1RCCKBRNPY1RNPY2RNPY4R
SCHEMBL30906509	0.94	NPY2R (0.62)	GLP1RCCKBRNPY1RNPY2RNPY4R
SCHEMBL31000947	0.93	NPY2R (0.61)	GLP1RCCKBRNPY1RNPY2RNPY4R
SCHEMBL29479816	0.91	NPY2R (0.68)	GLP1RCCKBRNPY1RNPY2RNPY4R
SCHEMBL30648451	0.91	CXCR4 (0.62)	GLP1RCCKBRNPY1RNPY2RNPY4R
SCHEMBL30277954	0.91	NPY2R (0.68)	GLP1RNPY1RNPY2RNPY4RNPY5R
SCHEMBL30648477	0.90	GLP1R (0.67)	GLP1RCCKBRNPY1RNPY2RNPY4R
SCHEMBL30906535	0.90	NPY2R (0.64)	GLP1RCCKBRNPY1RNPY2RNPY4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023019019-A2	HUMANIZATION, AFFINITY MATURATION, AND OPTIMIZATION METHODS FOR PROTEINS AND ANTIBODIES	ABWIZ BIO, INC. (US)	2023-02-16	—	—	WO	disclosed