SCHEMBL30648477

CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CS)NC(=O)[C@@H](NC(=O)[C@@H](N)CC(C)C)[C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.68

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	GLP1R	P43220	8/20	0.67

▸	CCKBR	P32239	4/20	0.67

▸	CALCR	P30988	4/20	0.65

▸	CXCR4	P61073	3/20	0.65

▸	NMBR	P28336	2/20	0.63

▸	GRPR	P30550	2/20	0.63

▸	GCGR	P47871	3/20	0.61

▸	C5AR1	P21730	1/20	0.60

▸	NPY1R	P25929	1/20	0.59

▸	NPY2R	P49146	1/20	0.59

▸	NPY4R	P50391	1/20	0.59

▸	NPY5R	Q15761	1/20	0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30277947	0.90	GLP1R (0.65)	GLP1RCCKBRCALCRNMBRGRPR
SCHEMBL31000923	0.90	GLP1R (0.68)	GLP1RCCKBRCALCRNMBRGRPR
SCHEMBL30432529	0.90	C5AR1 (0.67)	GLP1RCCKBRCALCRCXCR4NMBR
SCHEMBL30906533	0.89	GLP1R (0.62)	GLP1RCCKBRCALCRCXCR4NMBR
SCHEMBL31182946	0.89	GLP1R (0.64)	GLP1RCCKBRCALCRCXCR4GCGR
SCHEMBL30726588	0.89	GLP1R (0.63)	GLP1RCCKBRCALCRNMBRGRPR
SCHEMBL15987247	0.89	CXCR4 (0.81)	GLP1RCCKBRCXCR4GCGRC5AR1
SCHEMBL30658401	0.89	CALCR (0.75)	GLP1RCCKBRCALCRGCGRNPY1R
SCHEMBL31000889	0.88	GLP1R (0.71)	GLP1RCCKBRCALCRCXCR4NMBR
SCHEMBL30571153	0.88	NMBR (0.65)	GLP1RCCKBRCALCRCXCR4NMBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-116948034-B	Active type heterophagy antibody blocker Block-5S and preparation method thereof	南京珀尔泰生物技术有限公司	2024-06-25	—	—	CN	disclosed
CN-116948034-A	Active type heterophagy antibody blocker Block-5S and preparation method thereof	南京珀尔泰生物技术有限公司	2023-10-27	—	—	CN	disclosed