Sugi Predict

Sugi Predict / Compounds / SCHEMBL30277956

SCHEMBL30277956

SCHEMBL30277956

CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCNC(=N)N)[C@@H](C)O)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.72

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ EP300 Q09472 1/20 0.63
▸ HIF1A Q16665 1/20 0.63
▸ NMUR2 Q9GZQ4 3/20 0.59
▸ NMUR1 Q9HB89 3/20 0.59
▸ NPY2R P49146 7/20 0.59
▸ NPY4R P50391 7/20 0.59
▸ NPY5R Q15761 7/20 0.59
▸ NPY1R P25929 5/20 0.59
▸ KEAP1 Q14145 2/20 0.58
▸ TFPI P10646 2/20 0.57
▸ RAMP3 O60896 1/20 0.57
▸ CALCR P30988 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30648455 0.98 EP300 (0.64) EP300HIF1ANMUR2NMUR1NPY2R
SCHEMBL30277959 0.98 KEAP1 (0.60) EP300HIF1ANMUR2NMUR1NPY2R
SCHEMBL29479812 0.96 KEAP1 (0.60) EP300HIF1ANMUR2NMUR1NPY2R
SCHEMBL31000870 0.91 MAPK8 (0.67) EP300HIF1ANMUR2NMUR1NPY2R
SCHEMBL30262198 0.89 EP300 (0.64) EP300HIF1ANMUR2NMUR1NPY2R
SCHEMBL29562124 0.89 NPY2R (0.67) EP300HIF1ANMUR2NMUR1NPY2R
SCHEMBL30432659 0.88 EP300 (0.69) EP300HIF1ANMUR2NMUR1NPY2R
SCHEMBL30648475 0.88 GLP1R (0.61) TFPI
SCHEMBL31182641 0.88 MAPK8 (0.63) EP300HIF1ANMUR2NMUR1NPY2R
SCHEMBL30432021 0.88 NPY2R (0.68) EP300HIF1ANPY2RNPY4RNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630447-A2 ANTIBODIES OR FRAGMENTS THEREOF FOR SARS-COV-2 AND VARIANTS THEREOF Abwiz Bio, Inc. (US) 2025-10-15 — — EP disclosed
US-20240352445-A1 HUMANIZATION, AFFINITY MATURATION, AND OPTIMIZATION METHODS FOR PROTEINS AND ANTIBODIES ABWIZ BIO, INC. 2024-10-24 — — US disclosed
WO-2024124241-A2 ANTIBODIES OR FRAGMENTS THEREOF FOR SARS-COV-2 AND VARIANTS THEREOF ABWIZ BIO, INC. (US) 2024-06-13 — — WO disclosed
WO-2023019019-A2 HUMANIZATION, AFFINITY MATURATION, AND OPTIMIZATION METHODS FOR PROTEINS AND ANTIBODIES ABWIZ BIO, INC. (US) 2023-02-16 — — WO disclosed
Send feedback